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Flights from Knoxville to San Antonio
There are no direct flights from Knoxville to San Antonio. The fastest way is one stop via Atlanta or Dallas, about 3h 38m door to door (107 connections a week on current schedules).
No direct flights · 6 connection options From 3h 38m
Knoxville to San Antonio at a glance
Fastest journey3h 38mVia Atlanta, on current schedules
Nonstop flightsNoneConnect via Atlanta or Dallas
Best ways to fly from Knoxville to San Antonio
Ranked by how easy the connection is: one airline or alliance first (bags and connection protected), then the quickest self-transfer options.
1Search
TYS Atlanta (ATL) SAT
Leg 1: Delta Air Lines, American Airlines · Leg 2: Delta Air Lines, Frontier Airlines, Southwest Airlines
Sun10:45 TYS11:23 ATL0h 52m connection12:15 ATL13:23 SATDelta Air Lines
2Search
TYS Dallas (DFW) SAT
Leg 1: American Airlines · Leg 2: American Airlines, Envoy Air
Mon15:00 TYS15:57 DFW0h 48m connection16:45 DFW17:40 SATAmerican Airlines
3Search
TYS Nashville (BNA) SAT
Leg 1: Southwest Airlines · Leg 2: Southwest Airlines
Tue07:15 TYS06:50 BNA1h 25m connection08:15 BNA10:09 SATSouthwest Airlines
4Search
TYS Chicago (ORD) SAT
Leg 1: United Airlines, Envoy Air, GoJet Airlines · Leg 2: American Airlines, United Airlines, Volaris
Thu18:30 TYS19:00 ORD1h 00m connection20:00 ORD22:31 SATUnited Airlines
5Search
TYS Houston (IAH) SAT
Leg 1: Mesa Airlines · Leg 2: United Airlines, Mesa Airlines
Mon12:15 TYS13:10 IAH3h 35m connection16:45 IAH17:25 SATMesa Airlines
6Search
TYS Charlotte (CLT) SAT
Leg 1: American Airlines, Piedmont Airlines (1948-1989) · Leg 2: American Airlines
Mon11:00 TYS11:40 CLT3h 35m connection15:15 CLT16:43 SATPiedmont Airlines (1948-1989) + American Airlines
Connections are computed from flights actually flown over the last 8 weeks, with at least 45 minutes to change on one airline and 2 hours on separate tickets. Times are local. The search shows live itineraries and exact times.
Good to know
- Distance
- 1,543 km958 miles
- Journey time
- 3h 38mon current schedules
- Time difference
- -1hSan Antonio vs Knoxville
- Currency in San Antonio
- USD
- Airports
- TYS → SAT
Flights from Knoxville to San Antonio: questions answered
Are there direct flights from Knoxville to San Antonio?
No. There is no nonstop service, so you will connect, most easily in Atlanta, Dallas and Nashville. Some connections are on one airline or alliance, so your bags and connection are protected on a single ticket.
How long is the flight from Knoxville to San Antonio?
With one connection the journey usually takes around 3h 38m, depending on the layover. The straight-line distance is 1,543 km.
Where do you change planes between Knoxville and San Antonio?
The best connecting points are Atlanta (ATL), Dallas (DFW), Nashville (BNA) and Chicago (ORD). Delta Air Lines flies both legs via Atlanta, so you can book it as one ticket.
Which airports serve Knoxville and San Antonio?
Knoxville: McGhee Tyson Airport (TYS). San Antonio: San Antonio International Airport (SAT).
What is the time difference between Knoxville and San Antonio?
San Antonio is 1 hour behind Knoxville.





