Compare airlines and travel sites in one search No booking fees from us
FlightConnect
  1. Home
  2. Flights
  3. Flights from Knoxville
  4. Knoxville to Myrtle Beach
Connecting route · United States → United States

Flights from Knoxville to Myrtle Beach

There are no direct flights from Knoxville to Myrtle Beach. The fastest way is one stop via Atlanta or Nashville, about 2h 30m door to door (55 connections a week on current schedules).

No direct flights · 5 connection options From 2h 30m
TYSMYRATL

Knoxville to Myrtle Beach at a glance

Fastest journey2h 30mVia Atlanta, on current schedules
Nonstop flightsNoneConnect via Atlanta or Nashville

Best ways to fly from Knoxville to Myrtle Beach

Ranked by how easy the connection is: one airline or alliance first (bags and connection protected), then the quickest self-transfer options.

1
TYS Atlanta (ATL) MYR
Leg 1: Delta Air Lines, American Airlines · Leg 2: Delta Air Lines
Sun10:45 TYS11:23 ATL0h 52m connection12:15 ATL13:15 MYRDelta Air Lines
37 connections a week One airline, one ticket Fastest 2h 30m
Search
2
TYS Nashville (BNA) MYR
Leg 1: Southwest Airlines · Leg 2: Southwest Airlines
Sun18:15 TYS17:50 BNA1h 25m connection19:15 BNA21:22 MYRSouthwest Airlines
8 connections a week One airline, one ticket Fastest 3h 07m
Search
3
TYS Charlotte (CLT) MYR
Leg 1: American Airlines, Piedmont Airlines (1948-1989) · Leg 2: American Airlines
Sun16:15 TYS16:55 CLT2h 05m connection19:00 CLT19:41 MYRPiedmont Airlines (1948-1989) + American Airlines
4 connections a week One airline, one ticket Fastest 3h 26m
Search
4
TYS Baltimore (BWI) MYR
Leg 1: Southwest Airlines · Leg 2: Southwest Airlines
Mon08:30 TYS09:48 BWI2h 42m connection12:30 BWI13:39 MYRSouthwest Airlines
6 connections a week One airline, one ticket Fastest 5h 09m
Search
5
TYS Orlando (MCO) MYR
Leg 1: Allegiant Air, Southwest Airlines · Leg 2: Breeze Airways
Self-transfer likely ~5h 21m
Search

Connections are computed from flights actually flown over the last 8 weeks, with at least 45 minutes to change on one airline and 2 hours on separate tickets. Times are local. The search shows live itineraries and exact times.

Good to know

Distance
524 km325 miles
Journey time
2h 30mon current schedules
Time difference
NoneMyrtle Beach vs Knoxville
Currency in Myrtle Beach
USD
Airports
TYS → MYR

Flights from Knoxville to Myrtle Beach: questions answered

Are there direct flights from Knoxville to Myrtle Beach?
No. There is no nonstop service, so you will connect, most easily in Atlanta, Nashville and Charlotte. Some connections are on one airline or alliance, so your bags and connection are protected on a single ticket.
How long is the flight from Knoxville to Myrtle Beach?
With one connection the journey usually takes around 2h 30m, depending on the layover. The straight-line distance is 524 km.
Where do you change planes between Knoxville and Myrtle Beach?
The best connecting points are Atlanta (ATL), Nashville (BNA), Charlotte (CLT) and Baltimore (BWI). Delta Air Lines flies both legs via Atlanta, so you can book it as one ticket.
Which airports serve Knoxville and Myrtle Beach?
Knoxville: McGhee Tyson Airport (TYS). Myrtle Beach: Myrtle Beach International Airport (MYR).

More flights from Knoxville