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Flights from San Antonio to Knoxville
There are no direct flights from San Antonio to Knoxville. The fastest way is one stop via Nashville or Atlanta, about 3h 34m door to door (191 connections a week on current schedules).
No direct flights · 6 connection options From 3h 34m
San Antonio to Knoxville at a glance
Fastest journey3h 34mVia Nashville, on current schedules
Nonstop flightsNoneConnect via Nashville or Atlanta
Best ways to fly from San Antonio to Knoxville
Ranked by how easy the connection is: one airline or alliance first (bags and connection protected), then the quickest self-transfer options.
1Search
SAT Nashville (BNA) TYS
Leg 1: Southwest Airlines · Leg 2: Southwest Airlines
Sat07:00 SAT09:01 BNA0h 59m connection10:00 BNA11:34 TYSSouthwest Airlines
2Search
SAT Atlanta (ATL) TYS
Leg 1: Delta Air Lines, Frontier Airlines, Southwest Airlines · Leg 2: Delta Air Lines, American Airlines
Mon12:15 SAT15:26 ATL0h 49m connection16:15 ATL16:58 TYSDelta Air Lines
3Search
SAT Dallas (DFW) TYS
Leg 1: American Airlines · Leg 2: American Airlines
Tue08:00 SAT09:05 DFW0h 55m connection10:00 DFW12:51 TYSAmerican Airlines
4Search
SAT Houston (IAH) TYS
Leg 1: United Airlines, Mesa Airlines · Leg 2: Mesa Airlines
Mon11:45 SAT12:33 IAH2h 27m connection15:00 IAH17:49 TYSUnited Airlines + Mesa Airlines
5Search
SAT Charlotte (CLT) TYS
Leg 1: American Airlines · Leg 2: American Airlines, Piedmont Airlines (1948-1989), SkyWest
Mon07:45 SAT11:24 CLT2h 51m connection14:15 CLT14:55 TYSAmerican Airlines + Piedmont Airlines (1948-1989)
6Search
SAT Chicago (ORD) TYS
Leg 1: American Airlines, United Airlines · Leg 2: United Airlines, Envoy Air, GoJet Airlines
Mon15:15 SAT17:59 ORD2h 16m connection20:15 ORD22:40 TYSAmerican Airlines + United Airlines
Connections are computed from flights actually flown over the last 8 weeks, with at least 45 minutes to change on one airline and 2 hours on separate tickets. Times are local. The search shows live itineraries and exact times.
Good to know
- Distance
- 1,543 km958 miles
- Journey time
- 3h 34mon current schedules
- Time difference
- +1hKnoxville vs San Antonio
- Currency in Knoxville
- USD
- Airports
- SAT → TYS
Flights from San Antonio to Knoxville: questions answered
Are there direct flights from San Antonio to Knoxville?
No. There is no nonstop service, so you will connect, most easily in Nashville, Atlanta and Dallas. Some connections are on one airline or alliance, so your bags and connection are protected on a single ticket.
How long is the flight from San Antonio to Knoxville?
With one connection the journey usually takes around 3h 34m, depending on the layover. The straight-line distance is 1,543 km.
Where do you change planes between San Antonio and Knoxville?
The best connecting points are Nashville (BNA), Atlanta (ATL), Dallas (DFW) and Houston (IAH). Southwest Airlines flies both legs via Nashville, so you can book it as one ticket.
Which airports serve San Antonio and Knoxville?
San Antonio: San Antonio International Airport (SAT). Knoxville: McGhee Tyson Airport (TYS).
What is the time difference between San Antonio and Knoxville?
Knoxville is 1 hour ahead of San Antonio.





