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Flights from Knoxville to Louisville
There are no direct flights from Knoxville to Louisville. The fastest way is one stop via Atlanta or Nashville, about 2h 34m door to door (52 connections a week on current schedules).
No direct flights · 3 connection options From 2h 34m
Knoxville to Louisville at a glance
Fastest journey2h 34mVia Atlanta, on current schedules
Nonstop flightsNoneConnect via Atlanta or Nashville
Best ways to fly from Knoxville to Louisville
Ranked by how easy the connection is: one airline or alliance first (bags and connection protected), then the quickest self-transfer options.
1Search
TYS Atlanta (ATL) SDF
Leg 1: Delta Air Lines, American Airlines · Leg 2: Delta Air Lines
Mon12:15 TYS12:53 ATL0h 52m connection13:45 ATL14:49 SDFDelta Air Lines
2Search
TYS Nashville (BNA) SDF
Leg 1: Southwest Airlines · Leg 2: Southwest Airlines
Tue17:30 TYS17:05 BNA1h 55m connection19:00 BNA20:36 SDFSouthwest Airlines
3Search
TYS Charlotte (CLT) SDF
Leg 1: American Airlines, Piedmont Airlines (1948-1989) · Leg 2: American Airlines
Mon11:00 TYS11:40 CLT4h 20m connection16:00 CLT16:59 SDFPiedmont Airlines (1948-1989) + American Airlines
Connections are computed from flights actually flown over the last 8 weeks, with at least 45 minutes to change on one airline and 2 hours on separate tickets. Times are local. The search shows live itineraries and exact times.
Good to know
- Distance
- 303 km188 miles
- Journey time
- 2h 34mon current schedules
- Time difference
- NoneLouisville vs Knoxville
- Currency in Louisville
- USD
- Airports
- TYS → SDF
Flights from Knoxville to Louisville: questions answered
Are there direct flights from Knoxville to Louisville?
No. There is no nonstop service, so you will connect, most easily in Atlanta, Nashville and Charlotte. Some connections are on one airline or alliance, so your bags and connection are protected on a single ticket.
How long is the flight from Knoxville to Louisville?
With one connection the journey usually takes around 2h 34m, depending on the layover. The straight-line distance is 303 km.
Where do you change planes between Knoxville and Louisville?
The best connecting points are Atlanta (ATL), Nashville (BNA) and Charlotte (CLT). Delta Air Lines flies both legs via Atlanta, so you can book it as one ticket.
Which airports serve Knoxville and Louisville?
Knoxville: McGhee Tyson Airport (TYS). Louisville: Louisville Muhammad Ali International Airport (SDF).





