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Flights from Louisville to Knoxville
There are no direct flights from Louisville to Knoxville. The fastest way is one stop via Nashville or Atlanta, about 2h 34m door to door (81 connections a week on current schedules).
No direct flights · 3 connection options From 2h 34m
Louisville to Knoxville at a glance
Fastest journey2h 34mVia Nashville, on current schedules
Nonstop flightsNoneConnect via Nashville or Atlanta
Best ways to fly from Louisville to Knoxville
Ranked by how easy the connection is: one airline or alliance first (bags and connection protected), then the quickest self-transfer options.
1Search
SDF Nashville (BNA) TYS
Leg 1: Southwest Airlines · Leg 2: Southwest Airlines
Tue16:15 SDF15:54 BNA1h 21m connection17:15 BNA18:49 TYSSouthwest Airlines
2Search
SDF Atlanta (ATL) TYS
Leg 1: Delta Air Lines · Leg 2: Delta Air Lines, American Airlines
Mon08:15 SDF09:17 ATL0h 58m connection10:15 ATL10:58 TYSDelta Air Lines
3Search
SDF Charlotte (CLT) TYS
Leg 1: American Airlines · Leg 2: American Airlines, Piedmont Airlines (1948-1989), SkyWest
Mon10:00 SDF11:03 CLT3h 12m connection14:15 CLT14:55 TYSAmerican Airlines + Piedmont Airlines (1948-1989)
Connections are computed from flights actually flown over the last 8 weeks, with at least 45 minutes to change on one airline and 2 hours on separate tickets. Times are local. The search shows live itineraries and exact times.
Good to know
- Distance
- 303 km188 miles
- Journey time
- 2h 34mon current schedules
- Time difference
- NoneKnoxville vs Louisville
- Currency in Knoxville
- USD
- Airports
- SDF → TYS
Flights from Louisville to Knoxville: questions answered
Are there direct flights from Louisville to Knoxville?
No. There is no nonstop service, so you will connect, most easily in Nashville, Atlanta and Charlotte. Some connections are on one airline or alliance, so your bags and connection are protected on a single ticket.
How long is the flight from Louisville to Knoxville?
With one connection the journey usually takes around 2h 34m, depending on the layover. The straight-line distance is 303 km.
Where do you change planes between Louisville and Knoxville?
The best connecting points are Nashville (BNA), Atlanta (ATL) and Charlotte (CLT). Southwest Airlines flies both legs via Nashville, so you can book it as one ticket.
Which airports serve Louisville and Knoxville?
Louisville: Louisville Muhammad Ali International Airport (SDF). Knoxville: McGhee Tyson Airport (TYS).





