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Flights from Knoxville to Columbus
There are no direct flights from Knoxville to Columbus. The fastest way is one stop via Atlanta or Chicago, about 2h 49m door to door (91 connections a week on current schedules).
No direct flights · 6 connection options From 2h 49m
Knoxville to Columbus at a glance
Fastest journey2h 49mVia Atlanta, on current schedules
Nonstop flightsNoneConnect via Atlanta or Chicago
Best ways to fly from Knoxville to Columbus
Ranked by how easy the connection is: one airline or alliance first (bags and connection protected), then the quickest self-transfer options.
1Search
TYS Atlanta (ATL) CMH
Leg 1: Delta Air Lines, American Airlines · Leg 2: Delta Air Lines, Frontier Airlines, Southwest Airlines
Thu05:45 TYS06:23 ATL0h 52m connection07:15 ATL08:34 CMHDelta Air Lines
2Search
TYS Chicago (ORD) CMH
Leg 1: United Airlines, Envoy Air, GoJet Airlines · Leg 2: United Airlines, Envoy Air, Republic Airlines
Tue06:00 TYS06:30 ORD0h 45m connection07:15 ORD09:17 CMHUnited Airlines
3Search
TYS Nashville (BNA) CMH
Leg 1: Southwest Airlines · Leg 2: Southwest Airlines
Tue17:30 TYS17:05 BNA1h 55m connection19:00 BNA20:57 CMHSouthwest Airlines
4Search
TYS Baltimore (BWI) CMH
Leg 1: Southwest Airlines · Leg 2: Southwest Airlines
Wed08:15 TYS09:33 BWI1h 27m connection11:00 BWI12:05 CMHSouthwest Airlines
5Search
TYS Charlotte (CLT) CMH
Leg 1: American Airlines, Piedmont Airlines (1948-1989) · Leg 2: American Airlines
Mon09:15 TYS09:55 CLT2h 35m connection12:30 CLT13:30 CMHPiedmont Airlines (1948-1989) + American Airlines
6Search
TYS Washington (IAD) CMH
Leg 1: Allegiant Air, CommutAir · Leg 2: United Airlines, Mesa Airlines
Sun13:45 TYS15:05 IAD2h 25m connection17:30 IAD18:37 CMHCommutAir + United Airlines
Connections are computed from flights actually flown over the last 8 weeks, with at least 45 minutes to change on one airline and 2 hours on separate tickets. Times are local. The search shows live itineraries and exact times.
Good to know
- Distance
- 452 km281 miles
- Journey time
- 2h 49mon current schedules
- Time difference
- NoneColumbus vs Knoxville
- Currency in Columbus
- USD
- Airports
- TYS → CMH, LCK
Flights from Knoxville to Columbus: questions answered
Are there direct flights from Knoxville to Columbus?
No. There is no nonstop service, so you will connect, most easily in Atlanta, Chicago and Nashville. Some connections are on one airline or alliance, so your bags and connection are protected on a single ticket.
How long is the flight from Knoxville to Columbus?
With one connection the journey usually takes around 2h 49m, depending on the layover. The straight-line distance is 452 km.
Where do you change planes between Knoxville and Columbus?
The best connecting points are Atlanta (ATL), Chicago (ORD), Nashville (BNA) and Baltimore (BWI). Delta Air Lines flies both legs via Atlanta, so you can book it as one ticket.
Which airports serve Knoxville and Columbus?
Knoxville: McGhee Tyson Airport (TYS). Columbus: John Glenn Columbus International Airport (CMH) and Rickenbacker International Airport (LCK).





