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Flights from Columbus to Knoxville
There are no direct flights from Columbus to Knoxville. The fastest way is one stop via Atlanta or Baltimore, about 2h 43m door to door (158 connections a week on current schedules).
No direct flights · 6 connection options From 2h 43m
Columbus to Knoxville at a glance
Fastest journey2h 43mVia Atlanta, on current schedules
Nonstop flightsNoneConnect via Atlanta or Baltimore
Best ways to fly from Columbus to Knoxville
Ranked by how easy the connection is: one airline or alliance first (bags and connection protected), then the quickest self-transfer options.
1Search
CMH Atlanta (ATL) TYS
Leg 1: Delta Air Lines, Frontier Airlines, Southwest Airlines · Leg 2: Delta Air Lines, American Airlines
Mon08:15 CMH09:29 ATL0h 46m connection10:15 ATL10:58 TYSDelta Air Lines
2Search
CMH Baltimore (BWI) TYS
Leg 1: Southwest Airlines · Leg 2: Southwest Airlines
Thu16:30 CMH17:28 BWI1h 02m connection18:30 BWI19:49 TYSSouthwest Airlines
3Search
CMH Washington (IAD) TYS
Leg 1: United Airlines, Mesa Airlines, Republic Airlines · Leg 2: Allegiant Air, CommutAir, Mesa Airlines
Sat10:45 CMH11:49 IAD1h 11m connection13:00 IAD14:23 TYSMesa Airlines
4Search
CMH Chicago (ORD) TYS
Leg 1: United Airlines, Republic Airlines, Envoy Air · Leg 2: United Airlines, Envoy Air, GoJet Airlines
Sat14:15 CMH14:17 ORD1h 28m connection15:45 ORD18:00 TYSEnvoy Air
5Search
CMH Charlotte (CLT) TYS
Leg 1: American Airlines · Leg 2: American Airlines, Piedmont Airlines (1948-1989), SkyWest
Sat06:15 CMH07:17 CLT2h 13m connection09:30 CLT10:10 TYSAmerican Airlines + Piedmont Airlines (1948-1989)
6Search
CMH Nashville (BNA) TYS
Leg 1: Southwest Airlines · Leg 2: Southwest Airlines
Mon07:15 CMH07:13 BNA3h 17m connection10:30 BNA12:04 TYSSouthwest Airlines
Connections are computed from flights actually flown over the last 8 weeks, with at least 45 minutes to change on one airline and 2 hours on separate tickets. Times are local. The search shows live itineraries and exact times.
Good to know
- Distance
- 452 km281 miles
- Journey time
- 2h 43mon current schedules
- Time difference
- NoneKnoxville vs Columbus
- Currency in Knoxville
- USD
- Airports
- CMH, LCK → TYS
Flights from Columbus to Knoxville: questions answered
Are there direct flights from Columbus to Knoxville?
No. There is no nonstop service, so you will connect, most easily in Atlanta, Baltimore and Washington. Some connections are on one airline or alliance, so your bags and connection are protected on a single ticket.
How long is the flight from Columbus to Knoxville?
With one connection the journey usually takes around 2h 43m, depending on the layover. The straight-line distance is 452 km.
Where do you change planes between Columbus and Knoxville?
The best connecting points are Atlanta (ATL), Baltimore (BWI), Washington (IAD) and Chicago (ORD). Delta Air Lines flies both legs via Atlanta, so you can book it as one ticket.
Which airports serve Columbus and Knoxville?
Columbus: John Glenn Columbus International Airport (CMH) and Rickenbacker International Airport (LCK). Knoxville: McGhee Tyson Airport (TYS).





