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Flights from Knoxville to Charleston
There are no direct flights from Knoxville to Charleston. The fastest way is one stop via Atlanta or Charlotte, about 2h 25m door to door (61 connections a week on current schedules).
No direct flights · 6 connection options From 2h 25m
Knoxville to Charleston at a glance
Fastest journey2h 25mVia Atlanta, on current schedules
Nonstop flightsNoneConnect via Atlanta or Charlotte
Best ways to fly from Knoxville to Charleston
Ranked by how easy the connection is: one airline or alliance first (bags and connection protected), then the quickest self-transfer options.
1Search
TYS Atlanta (ATL) CHS
Leg 1: Delta Air Lines, American Airlines · Leg 2: Delta Air Lines
Mon10:30 TYS11:08 ATL0h 52m connection12:00 ATL12:55 CHSDelta Air Lines
2Search
TYS Charlotte (CLT) CHS
Leg 1: American Airlines, Piedmont Airlines (1948-1989) · Leg 2: American Airlines
Sun16:15 TYS16:55 CLT2h 05m connection19:00 CLT19:44 CHSPiedmont Airlines (1948-1989) + American Airlines
3Search
TYS Nashville (BNA) CHS
Leg 1: Southwest Airlines · Leg 2: Southwest Airlines
Sun18:15 TYS17:50 BNA2h 25m connection20:15 BNA22:22 CHSSouthwest Airlines
4Search
TYS Baltimore (BWI) CHS
Leg 1: Southwest Airlines · Leg 2: Southwest Airlines
Tue08:15 TYS09:33 BWI1h 27m connection11:00 BWI12:23 CHSSouthwest Airlines
5Search
TYS Washington (IAD) CHS
Leg 1: Allegiant Air, CommutAir · Leg 2: United Airlines, Republic Airlines
Mon13:45 TYS15:05 IAD2h 10m connection17:15 IAD18:47 CHSCommutAir + Republic Airlines
Connections are computed from flights actually flown over the last 8 weeks, with at least 45 minutes to change on one airline and 2 hours on separate tickets. Times are local. The search shows live itineraries and exact times.
Good to know
- Distance
- 509 km316 miles
- Journey time
- 2h 25mon current schedules
- Time difference
- NoneCharleston vs Knoxville
- Currency in Charleston
- USD
- Airports
- TYS → CHS
Flights from Knoxville to Charleston: questions answered
Are there direct flights from Knoxville to Charleston?
No. There is no nonstop service, so you will connect, most easily in Atlanta, Charlotte and Nashville. Some connections are on one airline or alliance, so your bags and connection are protected on a single ticket.
How long is the flight from Knoxville to Charleston?
With one connection the journey usually takes around 2h 25m, depending on the layover. The straight-line distance is 509 km.
Where do you change planes between Knoxville and Charleston?
The best connecting points are Atlanta (ATL), Charlotte (CLT), Nashville (BNA) and Baltimore (BWI). Delta Air Lines flies both legs via Atlanta, so you can book it as one ticket.
Which airports serve Knoxville and Charleston?
Knoxville: McGhee Tyson Airport (TYS). Charleston: Charleston International Airport (CHS).





