- Home
- Flights
- Flights from Charleston
- Charleston to Knoxville
Flights from Charleston to Knoxville
There are no direct flights from Charleston to Knoxville. The fastest way is one stop via Atlanta or Nashville, about 2h 28m door to door (109 connections a week on current schedules).
No direct flights · 6 connection options From 2h 28m
Charleston to Knoxville at a glance
Fastest journey2h 28mVia Atlanta, on current schedules
Nonstop flightsNoneConnect via Atlanta or Nashville
Best ways to fly from Charleston to Knoxville
Ranked by how easy the connection is: one airline or alliance first (bags and connection protected), then the quickest self-transfer options.
1Search
CHS Atlanta (ATL) TYS
Leg 1: Delta Air Lines · Leg 2: Delta Air Lines, American Airlines
Mon06:45 CHS07:36 ATL0h 54m connection08:30 ATL09:13 TYSDelta Air Lines
2Search
CHS Nashville (BNA) TYS
Leg 1: Southwest Airlines · Leg 2: Southwest Airlines
Mon14:45 CHS14:54 BNA2h 06m connection17:00 BNA18:34 TYSSouthwest Airlines
3Search
CHS Baltimore (BWI) TYS
Leg 1: Southwest Airlines · Leg 2: Southwest Airlines
Sun18:30 CHS19:41 BWI1h 19m connection21:00 BWI22:19 TYSSouthwest Airlines
4Search
CHS Charlotte (CLT) TYS
Leg 1: American Airlines · Leg 2: American Airlines, Piedmont Airlines (1948-1989), SkyWest
Mon10:30 CHS11:09 CLT3h 06m connection14:15 CLT14:55 TYSAmerican Airlines + Piedmont Airlines (1948-1989)
5Search
CHS Washington (IAD) TYS
Leg 1: United Airlines, Republic Airlines · Leg 2: Allegiant Air, CommutAir, Mesa Airlines
Sat06:15 CHS07:28 IAD5h 32m connection13:00 IAD14:23 TYSRepublic Airlines + Mesa Airlines
Connections are computed from flights actually flown over the last 8 weeks, with at least 45 minutes to change on one airline and 2 hours on separate tickets. Times are local. The search shows live itineraries and exact times.
Good to know
- Distance
- 509 km316 miles
- Journey time
- 2h 28mon current schedules
- Time difference
- NoneKnoxville vs Charleston
- Currency in Knoxville
- USD
- Airports
- CHS → TYS
Flights from Charleston to Knoxville: questions answered
Are there direct flights from Charleston to Knoxville?
No. There is no nonstop service, so you will connect, most easily in Atlanta, Nashville and Baltimore. Some connections are on one airline or alliance, so your bags and connection are protected on a single ticket.
How long is the flight from Charleston to Knoxville?
With one connection the journey usually takes around 2h 28m, depending on the layover. The straight-line distance is 509 km.
Where do you change planes between Charleston and Knoxville?
The best connecting points are Atlanta (ATL), Nashville (BNA), Baltimore (BWI) and Charlotte (CLT). Delta Air Lines flies both legs via Atlanta, so you can book it as one ticket.
Which airports serve Charleston and Knoxville?
Charleston: Charleston International Airport (CHS). Knoxville: McGhee Tyson Airport (TYS).





