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Flights from St Louis to Greenville
There are no direct flights from St Louis to Greenville. The fastest way is one stop via Atlanta or Nashville, about 2h 57m door to door (178 connections a week on current schedules).
No direct flights · 6 connection options From 2h 57m
St Louis to Greenville at a glance
Fastest journey2h 57mVia Atlanta, on current schedules
Nonstop flightsNoneConnect via Atlanta or Nashville
Best ways to fly from St Louis to Greenville
Ranked by how easy the connection is: one airline or alliance first (bags and connection protected), then the quickest self-transfer options.
1Search
STL Atlanta (ATL) GSP
Leg 1: Delta Air Lines, Frontier Airlines, Southwest Airlines · Leg 2: Delta Air Lines
Mon14:30 STL16:50 ATL0h 55m connection17:45 ATL18:27 GSPDelta Air Lines
2Search
STL Nashville (BNA) GSP
Leg 1: Southwest Airlines · Leg 2: Southwest Airlines
Mon17:45 STL18:38 BNA1h 22m connection20:00 BNA21:49 GSPSouthwest Airlines
3Search
STL Charlotte (CLT) GSP
Leg 1: American Airlines, Southwest Airlines · Leg 2: American Airlines
Mon15:30 STL18:05 CLT1h 10m connection19:15 CLT19:39 GSPAmerican Airlines
4Search
STL Detroit (DTW) GSP
Leg 1: Delta Air Lines, Southwest Airlines · Leg 2: Delta Air Lines
Sat16:00 STL18:16 DTW1h 44m connection20:00 DTW21:23 GSPDelta Air Lines
5Search
STL Chicago (ORD) GSP
Leg 1: American Airlines, United Airlines, GoJet Airlines · Leg 2: United Airlines, GoJet Airlines, Envoy Air
Sun07:30 STL08:39 ORD2h 06m connection10:45 ORD13:12 GSPAmerican Airlines + GoJet Airlines
Connections are computed from flights actually flown over the last 8 weeks, with at least 45 minutes to change on one airline and 2 hours on separate tickets. Times are local. The search shows live itineraries and exact times.
Good to know
- Distance
- 812 km504 miles
- Journey time
- 2h 57mon current schedules
- Time difference
- +1hGreenville vs St Louis
- Currency in Greenville
- USD
- Airports
- STL → GSP
Flights from St Louis to Greenville: questions answered
Are there direct flights from St Louis to Greenville?
No. There is no nonstop service, so you will connect, most easily in Atlanta, Nashville and Charlotte. Some connections are on one airline or alliance, so your bags and connection are protected on a single ticket.
How long is the flight from St Louis to Greenville?
With one connection the journey usually takes around 2h 57m, depending on the layover. The straight-line distance is 812 km.
Where do you change planes between St Louis and Greenville?
The best connecting points are Atlanta (ATL), Nashville (BNA), Charlotte (CLT) and Detroit (DTW). Delta Air Lines flies both legs via Atlanta, so you can book it as one ticket.
Which airports serve St Louis and Greenville?
St Louis: St. Louis Lambert International Airport (STL). Greenville: Greenville-Spartanburg International Airport (GSP).
What is the time difference between St Louis and Greenville?
Greenville is 1 hour ahead of St Louis.





