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Flights from Greenville to St Louis
There are no direct flights from Greenville to St Louis. The fastest way is one stop via Atlanta or Nashville, about 2h 56m door to door (107 connections a week on current schedules).
No direct flights · 6 connection options From 2h 56m
Greenville to St Louis at a glance
Fastest journey2h 56mVia Atlanta, on current schedules
Nonstop flightsNoneConnect via Atlanta or Nashville
Best ways to fly from Greenville to St Louis
Ranked by how easy the connection is: one airline or alliance first (bags and connection protected), then the quickest self-transfer options.
1Search
GSP Atlanta (ATL) STL
Leg 1: Delta Air Lines · Leg 2: Delta Air Lines, Frontier Airlines, Southwest Airlines
Mon06:00 GSP06:38 ATL0h 52m connection07:30 ATL07:56 STLDelta Air Lines
2Search
GSP Nashville (BNA) STL
Leg 1: Southwest Airlines · Leg 2: Southwest Airlines
Sat06:45 GSP06:35 BNA1h 25m connection08:00 BNA08:50 STLSouthwest Airlines
3Search
GSP Charlotte (CLT) STL
Leg 1: American Airlines, Piedmont Airlines (1948-1989) · Leg 2: American Airlines, Southwest Airlines
Sun21:00 GSP21:29 CLT2h 01m connection23:30 CLT00:01 STLAmerican Airlines
4Search
GSP Columbus (CMH) STL
Leg 1: Breeze Airways · Leg 2: Southwest Airlines
Mon16:30 GSP17:31 CMH2h 29m connection20:00 CMH20:06 STLBreeze Airways + Southwest Airlines
5Search
GSP Chicago (ORD) STL
Leg 1: United Airlines, GoJet Airlines, Envoy Air · Leg 2: American Airlines, United Airlines, GoJet Airlines
Sun06:15 GSP06:52 ORD2h 08m connection09:00 ORD09:59 STLEnvoy Air + American Airlines
6Search
GSP Detroit (DTW) STL
Leg 1: Delta Air Lines · Leg 2: Delta Air Lines, Southwest Airlines
Mon07:15 GSP08:36 DTW3h 54m connection12:30 DTW12:51 STLDelta Air Lines
Connections are computed from flights actually flown over the last 8 weeks, with at least 45 minutes to change on one airline and 2 hours on separate tickets. Times are local. The search shows live itineraries and exact times.
Good to know
- Distance
- 812 km504 miles
- Journey time
- 2h 56mon current schedules
- Time difference
- -1hSt Louis vs Greenville
- Currency in St Louis
- USD
- Airports
- GSP → STL
Flights from Greenville to St Louis: questions answered
Are there direct flights from Greenville to St Louis?
No. There is no nonstop service, so you will connect, most easily in Atlanta, Nashville and Charlotte. Some connections are on one airline or alliance, so your bags and connection are protected on a single ticket.
How long is the flight from Greenville to St Louis?
With one connection the journey usually takes around 2h 56m, depending on the layover. The straight-line distance is 812 km.
Where do you change planes between Greenville and St Louis?
The best connecting points are Atlanta (ATL), Nashville (BNA), Charlotte (CLT) and Columbus (CMH). Delta Air Lines flies both legs via Atlanta, so you can book it as one ticket.
Which airports serve Greenville and St Louis?
Greenville: Greenville-Spartanburg International Airport (GSP). St Louis: St. Louis Lambert International Airport (STL).
What is the time difference between Greenville and St Louis?
St Louis is 1 hour behind Greenville.





