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Flights from Sioux Falls to Panama City
There are no direct flights from Sioux Falls to Panama City. The fastest way is one stop via Atlanta or Denver, about 4h 52m door to door (27 connections a week on current schedules).
No direct flights · 5 connection options From 4h 52m
Sioux Falls to Panama City at a glance
Fastest journey4h 52mVia Atlanta, on current schedules
Nonstop flightsNoneConnect via Atlanta or Denver
Best ways to fly from Sioux Falls to Panama City
Ranked by how easy the connection is: one airline or alliance first (bags and connection protected), then the quickest self-transfer options.
1Search
FSD Atlanta (ATL) ECP
Leg 1: Delta Air Lines · Leg 2: Delta Air Lines
Mon05:30 FSD08:45 ATL1h 45m connection10:30 ATL10:22 ECPDelta Air Lines
2Search
FSD Denver (DEN) ECP
Leg 1: Frontier Airlines, United Airlines, SkyWest · Leg 2: Southwest Airlines, United Airlines
Sun11:30 FSD12:05 DEN2h 10m connection14:15 DEN17:52 ECPSkyWest + Southwest Airlines
3Search
FSD Dallas (DFW) ECP
Leg 1: American Airlines · Leg 2: American Airlines, Envoy Air
Thu07:30 FSD09:30 DFW2h 45m connection12:15 DFW13:58 ECPAmerican Airlines
4Search
FSD Nashville (BNA) ECP
Leg 1: Allegiant Air · Leg 2: Southwest Airlines
Mon09:45 FSD11:32 BNA6h 28m connection18:00 BNA19:02 ECPAllegiant Air + Southwest Airlines
Connections are computed from flights actually flown over the last 8 weeks, with at least 45 minutes to change on one airline and 2 hours on separate tickets. Times are local. The search shows live itineraries and exact times.
Good to know
- Distance
- 1,781 km1,106 miles
- Journey time
- 4h 52mon current schedules
- Time difference
- NonePanama City vs Sioux Falls
- Currency in Panama City
- USD
- Airports
- FSD → ECP
Flights from Sioux Falls to Panama City: questions answered
Are there direct flights from Sioux Falls to Panama City?
No. There is no nonstop service, so you will connect, most easily in Atlanta, Denver and Dallas. Some connections are on one airline or alliance, so your bags and connection are protected on a single ticket.
How long is the flight from Sioux Falls to Panama City?
With one connection the journey usually takes around 4h 52m, depending on the layover. The straight-line distance is 1,781 km.
Where do you change planes between Sioux Falls and Panama City?
The best connecting points are Atlanta (ATL), Denver (DEN), Dallas (DFW) and Nashville (BNA). Delta Air Lines flies both legs via Atlanta, so you can book it as one ticket.
Which airports serve Sioux Falls and Panama City?
Sioux Falls: Sioux Falls Regional Airport (FSD). Panama City: Northwest Florida Beaches International Airport (ECP).





