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Flights from Panama City to Sioux Falls
There are no direct flights from Panama City to Sioux Falls. The fastest way is one stop via Dallas or Denver, about 5h 24m door to door (8 connections a week on current schedules).
No direct flights · 5 connection options From 4h 54m
Panama City to Sioux Falls at a glance
Fastest journey4h 54mVia Dallas, on current schedules
Nonstop flightsNoneConnect via Dallas or Denver
Best ways to fly from Panama City to Sioux Falls
Ranked by how easy the connection is: one airline or alliance first (bags and connection protected), then the quickest self-transfer options.
1Search
ECP Dallas (DFW) FSD
Leg 1: American Airlines, Envoy Air · Leg 2: American Airlines, Envoy Air
Tue15:30 ECP17:26 DFW1h 34m connection19:00 DFW20:54 FSDAmerican Airlines
2Search
ECP Denver (DEN) FSD
Leg 1: Southwest Airlines, United Airlines · Leg 2: Frontier Airlines, United Airlines, SkyWest
Sat12:45 ECP14:33 DEN3h 27m connection18:00 DEN20:22 FSDSouthwest Airlines + United Airlines
3Search
ECP Chicago (ORD) FSD
Leg 1: United Airlines, Republic Airlines · Leg 2: United Airlines, Envoy Air, GoJet Airlines
Sat14:15 ECP16:19 ORD5h 41m connection22:00 ORD23:26 FSDRepublic Airlines + United Airlines
Connections are computed from flights actually flown over the last 8 weeks, with at least 45 minutes to change on one airline and 2 hours on separate tickets. Times are local. The search shows live itineraries and exact times.
Good to know
- Distance
- 1,781 km1,106 miles
- Journey time
- 4h 54mon current schedules
- Time difference
- NoneSioux Falls vs Panama City
- Currency in Sioux Falls
- USD
- Airports
- ECP → FSD
Flights from Panama City to Sioux Falls: questions answered
Are there direct flights from Panama City to Sioux Falls?
No. There is no nonstop service, so you will connect, most easily in Dallas, Denver and Chicago. Some connections are on one airline or alliance, so your bags and connection are protected on a single ticket.
How long is the flight from Panama City to Sioux Falls?
With one connection the journey usually takes around 4h 54m, depending on the layover. The straight-line distance is 1,781 km.
Where do you change planes between Panama City and Sioux Falls?
The best connecting points are Dallas (DFW), Denver (DEN), Chicago (ORD) and Atlanta (ATL). American Airlines flies both legs via Dallas, so you can book it as one ticket.
Which airports serve Panama City and Sioux Falls?
Panama City: Northwest Florida Beaches International Airport (ECP). Sioux Falls: Sioux Falls Regional Airport (FSD).





