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Flights from Louisville to Cape Girardeau
There are no direct flights from Louisville to Cape Girardeau. The fastest way is one stop via Chicago, about 4h 15m door to door (5 connections a week on current schedules).
No direct flights · 1 connection option From 4h 15m
Louisville to Cape Girardeau at a glance
Fastest journey4h 15mVia Chicago, on current schedules
Nonstop flightsNoneConnect via Chicago
Best ways to fly from Louisville to Cape Girardeau
Ranked by how easy the connection is: one airline or alliance first (bags and connection protected), then the quickest self-transfer options.
1Search
SDF Chicago (ORD) CGI
Leg 1: Republic Airlines, SkyWest, Envoy Air · Leg 2: Contour Airlines
Mon10:15 SDF10:21 ORD2h 09m connection12:30 ORD13:30 CGIRepublic Airlines + Contour Airlines
Connections are computed from flights actually flown over the last 8 weeks, with at least 45 minutes to change on one airline and 2 hours on separate tickets. Times are local. The search shows live itineraries and exact times.
Good to know
- Distance
- 354 km220 miles
- Journey time
- 4h 15mon current schedules
- Time difference
- -1hCape Girardeau vs Louisville
- Currency in Cape Girardeau
- USD
- Airports
- SDF → CGI
Flights from Louisville to Cape Girardeau: questions answered
Are there direct flights from Louisville to Cape Girardeau?
No. There is no nonstop service, so you will connect, most easily in Chicago. Most connections mean separate tickets, so leave plenty of time to collect bags and check in again.
How long is the flight from Louisville to Cape Girardeau?
With one connection the journey usually takes around 4h 15m, depending on the layover. The straight-line distance is 354 km.
Where do you change planes between Louisville and Cape Girardeau?
The best connecting points are Chicago (ORD). Compare one-ticket itineraries with self-transfer options in the search.
Which airports serve Louisville and Cape Girardeau?
Louisville: Louisville Muhammad Ali International Airport (SDF). Cape Girardeau: Cape Girardeau Regional Airport (CGI).
What is the time difference between Louisville and Cape Girardeau?
Cape Girardeau is 1 hour behind Louisville.





