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Flights from Cape Girardeau to Louisville
There are no direct flights from Cape Girardeau to Louisville. The fastest way is one stop via Chicago, about 4h 59m door to door (3 connections a week on current schedules).
No direct flights · 1 connection option From 4h 59m
Cape Girardeau to Louisville at a glance
Fastest journey4h 59mVia Chicago, on current schedules
Nonstop flightsNoneConnect via Chicago
Best ways to fly from Cape Girardeau to Louisville
Ranked by how easy the connection is: one airline or alliance first (bags and connection protected), then the quickest self-transfer options.
1Search
CGI Chicago (ORD) SDF
Leg 1: Contour Airlines · Leg 2: Republic Airlines, SkyWest, GoJet Airlines
Mon10:00 CGI11:12 ORD2h 48m connection14:00 ORD15:59 SDFContour Airlines + Republic Airlines
Connections are computed from flights actually flown over the last 8 weeks, with at least 45 minutes to change on one airline and 2 hours on separate tickets. Times are local. The search shows live itineraries and exact times.
Good to know
- Distance
- 354 km220 miles
- Journey time
- 4h 59mon current schedules
- Time difference
- +1hLouisville vs Cape Girardeau
- Currency in Louisville
- USD
- Airports
- CGI → SDF
Flights from Cape Girardeau to Louisville: questions answered
Are there direct flights from Cape Girardeau to Louisville?
No. There is no nonstop service, so you will connect, most easily in Chicago. Most connections mean separate tickets, so leave plenty of time to collect bags and check in again.
How long is the flight from Cape Girardeau to Louisville?
With one connection the journey usually takes around 4h 59m, depending on the layover. The straight-line distance is 354 km.
Where do you change planes between Cape Girardeau and Louisville?
The best connecting points are Chicago (ORD). Compare one-ticket itineraries with self-transfer options in the search.
Which airports serve Cape Girardeau and Louisville?
Cape Girardeau: Cape Girardeau Regional Airport (CGI). Louisville: Louisville Muhammad Ali International Airport (SDF).
What is the time difference between Cape Girardeau and Louisville?
Louisville is 1 hour ahead of Cape Girardeau.





