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Flights from Knoxville to Sioux Falls
There are no direct flights from Knoxville to Sioux Falls. The fastest way is one stop via Chicago or Dallas, about 4h 49m door to door (42 connections a week on current schedules).
No direct flights · 5 connection options From 4h 43m
Knoxville to Sioux Falls at a glance
Fastest journey4h 43mVia Chicago, on current schedules
Nonstop flightsNoneConnect via Chicago or Dallas
Best ways to fly from Knoxville to Sioux Falls
Ranked by how easy the connection is: one airline or alliance first (bags and connection protected), then the quickest self-transfer options.
1Search
TYS Chicago (ORD) FSD
Leg 1: United Airlines, Envoy Air, GoJet Airlines · Leg 2: United Airlines, Envoy Air, GoJet Airlines
Sun06:15 TYS06:45 ORD2h 00m connection08:45 ORD10:04 FSDUnited Airlines + GoJet Airlines
2Search
TYS Dallas (DFW) FSD
Leg 1: American Airlines · Leg 2: American Airlines, Envoy Air
Sun18:00 TYS18:57 DFW1h 03m connection20:00 DFW21:54 FSDAmerican Airlines
3Search
TYS Denver (DEN) FSD
Leg 1: Allegiant Air, Frontier Airlines, Southwest Airlines · Leg 2: Frontier Airlines, United Airlines, SkyWest
Sat14:00 TYS14:44 DEN3h 16m connection18:00 DEN20:22 FSDSouthwest Airlines + United Airlines
Connections are computed from flights actually flown over the last 8 weeks, with at least 45 minutes to change on one airline and 2 hours on separate tickets. Times are local. The search shows live itineraries and exact times.
Good to know
- Distance
- 1,379 km856 miles
- Journey time
- 4h 43mon current schedules
- Time difference
- -1hSioux Falls vs Knoxville
- Currency in Sioux Falls
- USD
- Airports
- TYS → FSD
Flights from Knoxville to Sioux Falls: questions answered
Are there direct flights from Knoxville to Sioux Falls?
No. There is no nonstop service, so you will connect, most easily in Chicago, Dallas and Denver. Some connections are on one airline or alliance, so your bags and connection are protected on a single ticket.
How long is the flight from Knoxville to Sioux Falls?
With one connection the journey usually takes around 4h 43m, depending on the layover. The straight-line distance is 1,379 km.
Where do you change planes between Knoxville and Sioux Falls?
The best connecting points are Chicago (ORD), Dallas (DFW), Denver (DEN) and Atlanta (ATL). United Airlines flies both legs via Chicago, so you can book it as one ticket.
Which airports serve Knoxville and Sioux Falls?
Knoxville: McGhee Tyson Airport (TYS). Sioux Falls: Sioux Falls Regional Airport (FSD).
What is the time difference between Knoxville and Sioux Falls?
Sioux Falls is 1 hour behind Knoxville.





