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Flights from Knoxville to San Francisco
There are no direct flights from Knoxville to San Francisco. The fastest way is one stop via Denver or Dallas, about 6h 16m door to door (124 connections a week on current schedules).
No direct flights · 6 connection options From 6h 16m
Knoxville to San Francisco at a glance
Fastest journey6h 16mVia Denver, on current schedules
Nonstop flightsNoneConnect via Denver or Dallas
Best ways to fly from Knoxville to San Francisco
Ranked by how easy the connection is: one airline or alliance first (bags and connection protected), then the quickest self-transfer options.
1Search
TYS Denver (DEN) SFO
Leg 1: Allegiant Air, Frontier Airlines, Southwest Airlines · Leg 2: Frontier Airlines, Southwest Airlines, United Airlines
Fri17:00 TYS17:44 DEN1h 01m connection18:45 DEN20:16 SFOSouthwest Airlines
2Search
TYS Dallas (DFW) SFO
Leg 1: American Airlines · Leg 2: American Airlines, Frontier Airlines, United Airlines
Tue17:45 TYS18:42 DFW0h 48m connection19:30 DFW21:03 SFOAmerican Airlines
3Search
TYS Atlanta (ATL) SFO
Leg 1: Delta Air Lines, American Airlines · Leg 2: Delta Air Lines, Frontier Airlines, United Airlines
Thu12:30 TYS13:08 ATL0h 52m connection14:00 ATL15:51 SFODelta Air Lines
4Search
TYS Nashville (BNA) SFO
Leg 1: Southwest Airlines · Leg 2: Southwest Airlines, United Airlines
Fri18:15 TYS17:50 BNA1h 40m connection19:30 BNA21:52 SFOSouthwest Airlines
5Search
TYS Chicago (ORD) SFO
Leg 1: United Airlines, Envoy Air, GoJet Airlines · Leg 2: American Airlines, United Airlines
Mon06:15 TYS06:45 ORD1h 00m connection07:45 ORD10:10 SFOUnited Airlines
6Search
TYS Austin (AUS) SFO
Leg 1: Allegiant Air, Southwest Airlines · Leg 2: Delta Air Lines, Southwest Airlines, United Airlines
Fri08:15 TYS09:22 AUS4h 23m connection13:45 AUS15:21 SFOAllegiant Air + United Airlines
Connections are computed from flights actually flown over the last 8 weeks, with at least 45 minutes to change on one airline and 2 hours on separate tickets. Times are local. The search shows live itineraries and exact times.
Good to know
- Distance
- 3,407 km2,116 miles
- Journey time
- 6h 16mon current schedules
- Time difference
- -3hSan Francisco vs Knoxville
- Currency in San Francisco
- USD
- Airports
- TYS → SFO
Flights from Knoxville to San Francisco: questions answered
Are there direct flights from Knoxville to San Francisco?
No. There is no nonstop service, so you will connect, most easily in Denver, Dallas and Atlanta. Some connections are on one airline or alliance, so your bags and connection are protected on a single ticket.
How long is the flight from Knoxville to San Francisco?
With one connection the journey usually takes around 6h 16m, depending on the layover. The straight-line distance is 3,407 km.
Where do you change planes between Knoxville and San Francisco?
The best connecting points are Denver (DEN), Dallas (DFW), Atlanta (ATL) and Nashville (BNA). Allegiant Air flies both legs via Denver, so you can book it as one ticket.
Which airports serve Knoxville and San Francisco?
Knoxville: McGhee Tyson Airport (TYS). San Francisco: San Francisco International Airport (SFO).
What is the time difference between Knoxville and San Francisco?
San Francisco is 3 hours behind Knoxville.





