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Flights from Knoxville to La Crosse
There are no direct flights from Knoxville to La Crosse. The fastest way is one stop via Chicago, about 11h 09m door to door (2 connections a week on current schedules).
No direct flights · 1 connection option From 11h 09m
Knoxville to La Crosse at a glance
Fastest journey11h 09mVia Chicago, on current schedules
Nonstop flightsNoneConnect via Chicago
Best ways to fly from Knoxville to La Crosse
Ranked by how easy the connection is: one airline or alliance first (bags and connection protected), then the quickest self-transfer options.
1Search
TYS Chicago (ORD) LSE
Leg 1: United Airlines, Envoy Air, GoJet Airlines · Leg 2: Envoy Air
Mon07:45 TYS08:08 ORD8h 52m connection17:00 ORD17:54 LSERepublic Airlines + Envoy Air
Connections are computed from flights actually flown over the last 8 weeks, with at least 45 minutes to change on one airline and 2 hours on separate tickets. Times are local. The search shows live itineraries and exact times.
Good to know
- Distance
- 1,073 km666 miles
- Journey time
- 11h 09mon current schedules
- Time difference
- -1hLa Crosse vs Knoxville
- Currency in La Crosse
- USD
- Airports
- TYS → LSE
Flights from Knoxville to La Crosse: questions answered
Are there direct flights from Knoxville to La Crosse?
No. There is no nonstop service, so you will connect, most easily in Chicago. Some connections are on one airline or alliance, so your bags and connection are protected on a single ticket.
How long is the flight from Knoxville to La Crosse?
With one connection the journey usually takes around 11h 09m, depending on the layover. The straight-line distance is 1,073 km.
Where do you change planes between Knoxville and La Crosse?
The best connecting points are Chicago (ORD). United Airlines flies both legs via Chicago, so you can book it as one ticket.
Which airports serve Knoxville and La Crosse?
Knoxville: McGhee Tyson Airport (TYS). La Crosse: La Crosse Regional Airport (LSE).
What is the time difference between Knoxville and La Crosse?
La Crosse is 1 hour behind Knoxville.





