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Flights from Knoxville to Indianapolis
There are no direct flights from Knoxville to Indianapolis. The fastest way is one stop via Atlanta or Nashville, about 2h 46m door to door (79 connections a week on current schedules).
No direct flights · 4 connection options From 2h 46m
Knoxville to Indianapolis at a glance
Fastest journey2h 46mVia Atlanta, on current schedules
Nonstop flightsNoneConnect via Atlanta or Nashville
Best ways to fly from Knoxville to Indianapolis
Ranked by how easy the connection is: one airline or alliance first (bags and connection protected), then the quickest self-transfer options.
1Search
TYS Atlanta (ATL) IND
Leg 1: Delta Air Lines, American Airlines · Leg 2: Delta Air Lines, Frontier Airlines, Southwest Airlines
Mon20:15 TYS20:53 ATL0h 52m connection21:45 ATL23:01 INDDelta Air Lines
2Search
TYS Nashville (BNA) IND
Leg 1: Southwest Airlines · Leg 2: Southwest Airlines
Sun18:15 TYS17:50 BNA1h 25m connection19:15 BNA21:04 INDSouthwest Airlines
3Search
TYS Charlotte (CLT) IND
Leg 1: American Airlines, Piedmont Airlines (1948-1989) · Leg 2: American Airlines
Mon11:00 TYS11:40 CLT2h 20m connection14:00 CLT15:12 INDPiedmont Airlines (1948-1989) + American Airlines
4Search
TYS Chicago (ORD) IND
Leg 1: United Airlines, Envoy Air, GoJet Airlines · Leg 2: American Airlines, United Airlines, SkyWest
Mon06:15 TYS06:45 ORD2h 00m connection08:45 ORD10:29 INDUnited Airlines + Republic Airlines
Connections are computed from flights actually flown over the last 8 weeks, with at least 45 minutes to change on one airline and 2 hours on separate tickets. Times are local. The search shows live itineraries and exact times.
Good to know
- Distance
- 467 km290 miles
- Journey time
- 2h 46mon current schedules
- Time difference
- NoneIndianapolis vs Knoxville
- Currency in Indianapolis
- USD
- Airports
- TYS → IND
Flights from Knoxville to Indianapolis: questions answered
Are there direct flights from Knoxville to Indianapolis?
No. There is no nonstop service, so you will connect, most easily in Atlanta, Nashville and Charlotte. Some connections are on one airline or alliance, so your bags and connection are protected on a single ticket.
How long is the flight from Knoxville to Indianapolis?
With one connection the journey usually takes around 2h 46m, depending on the layover. The straight-line distance is 467 km.
Where do you change planes between Knoxville and Indianapolis?
The best connecting points are Atlanta (ATL), Nashville (BNA), Charlotte (CLT) and Chicago (ORD). Delta Air Lines flies both legs via Atlanta, so you can book it as one ticket.
Which airports serve Knoxville and Indianapolis?
Knoxville: McGhee Tyson Airport (TYS). Indianapolis: Indianapolis International Airport (IND).





