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Connecting route · United States → United States

Flights from Des Moines to St Louis

There are no direct flights from Des Moines to St Louis. The fastest way is one stop via Chicago or Nashville, about 3h 31m door to door (41 connections a week on current schedules).

No direct flights · 2 connection options From 3h 31m
DSMSTLORD

Des Moines to St Louis at a glance

Fastest journey3h 31mVia Chicago, on current schedules
Nonstop flightsNoneConnect via Chicago or Nashville

Best ways to fly from Des Moines to St Louis

Ranked by how easy the connection is: one airline or alliance first (bags and connection protected), then the quickest self-transfer options.

1
DSM Chicago (ORD) STL
Leg 1: American Airlines, United Airlines, SkyWest · Leg 2: American Airlines, United Airlines, GoJet Airlines
Wed08:00 DSM09:21 ORD1h 09m connection10:30 ORD11:31 STLUnited Airlines
37 connections a week One airline, one ticket Fastest 3h 31m
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2
DSM Nashville (BNA) STL
Leg 1: Allegiant Air · Leg 2: Southwest Airlines
Sun09:30 DSM10:51 BNA2h 24m connection13:15 BNA14:05 STLAllegiant Air + Southwest Airlines
4 connections a weekSelf-transfer likely Fastest 4h 35m
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Connections are computed from flights actually flown over the last 8 weeks, with at least 45 minutes to change on one airline and 2 hours on separate tickets. Times are local. The search shows live itineraries and exact times.

Good to know

Distance
439 km273 miles
Journey time
3h 31mon current schedules
Time difference
NoneSt Louis vs Des Moines
Currency in St Louis
USD
Airports
DSM → STL

Flights from Des Moines to St Louis: questions answered

Are there direct flights from Des Moines to St Louis?
No. There is no nonstop service, so you will connect, most easily in Chicago and Nashville. Some connections are on one airline or alliance, so your bags and connection are protected on a single ticket.
How long is the flight from Des Moines to St Louis?
With one connection the journey usually takes around 3h 31m, depending on the layover. The straight-line distance is 439 km.
Where do you change planes between Des Moines and St Louis?
The best connecting points are Chicago (ORD) and Nashville (BNA). American Airlines flies both legs via Chicago, so you can book it as one ticket.
Which airports serve Des Moines and St Louis?
Des Moines: Des Moines International Airport (DSM). St Louis: St. Louis Lambert International Airport (STL).

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