Compare airlines and travel sites in one search No booking fees from us
FlightConnect
Search flights
  1. Home
  2. Flights
  3. Flights from Des Moines
  4. Des Moines to Louisville
Connecting route · United States → United States

Flights from Des Moines to Louisville

There are no direct flights from Des Moines to Louisville. The fastest way is one stop via Nashville or Chicago, about 4h 21m door to door (20 connections a week on current schedules).

No direct flights · 2 connection options From 4h 21m
DSMSDFORD

Des Moines to Louisville at a glance

Fastest journey4h 21mVia Nashville, on current schedules
Nonstop flightsNoneConnect via Nashville or Chicago

Best ways to fly from Des Moines to Louisville

Ranked by how easy the connection is: one airline or alliance first (bags and connection protected), then the quickest self-transfer options.

1
DSM Nashville (BNA) SDF
Leg 1: Allegiant Air · Leg 2: Southwest Airlines
Sun08:30 DSM09:51 BNA2h 24m connection12:15 BNA13:51 SDFAllegiant Air + Southwest Airlines
4 connections a weekSelf-transfer likely Fastest 4h 21m
Search
2
DSM Chicago (ORD) SDF
Leg 1: American Airlines, United Airlines, SkyWest · Leg 2: Republic Airlines, SkyWest, GoJet Airlines
Sun07:30 DSM08:45 ORD2h 15m connection11:00 ORD12:55 SDFRepublic Airlines + SkyWest
16 connections a week One airline, one ticket Fastest 4h 25m
Search

Connections are computed from flights actually flown over the last 8 weeks, with at least 45 minutes to change on one airline and 2 hours on separate tickets. Times are local. The search shows live itineraries and exact times.

Good to know

Distance
766 km476 miles
Journey time
4h 21mon current schedules
Time difference
+1hLouisville vs Des Moines
Currency in Louisville
USD
Airports
DSM → SDF

Flights from Des Moines to Louisville: questions answered

Are there direct flights from Des Moines to Louisville?
No. There is no nonstop service, so you will connect, most easily in Nashville and Chicago. Some connections are on one airline or alliance, so your bags and connection are protected on a single ticket.
How long is the flight from Des Moines to Louisville?
With one connection the journey usually takes around 4h 21m, depending on the layover. The straight-line distance is 766 km.
Where do you change planes between Des Moines and Louisville?
The best connecting points are Nashville (BNA) and Chicago (ORD). Compare one-ticket itineraries with self-transfer options in the search.
Which airports serve Des Moines and Louisville?
Des Moines: Des Moines International Airport (DSM). Louisville: Louisville Muhammad Ali International Airport (SDF).
What is the time difference between Des Moines and Louisville?
Louisville is 1 hour ahead of Des Moines.

More flights from Des Moines

The reflective Cloud Gate sculpture in Chicago surrounded by iconic skyscrapers.NonstopChicagoNonstopOne-way fromUS$127Stunning view of Denver's cityscape with skyscrapers under a colorful sunset sky.NonstopDenverNonstopOne-way fromUS$145Scenic view of İstanbul's historic architecture along the Bosphorus showcasing Galata Tower.1+ stopIstanbulWith a connectionOne-way fromUS$525A captivating view of Atlanta's skyline with illuminated buildings and highways at night.NonstopAtlantaNonstopSee the best way to goThe Toronto skyline and CN Tower at dusk1+ stopTorontoWith a connectionSee the best way to goA vibrant view of Baltimore cityscape featuring iconic skyscrapers under a clear sky.1+ stopBaltimoreWith a connectionSee the best way to go