- Home
- Flights
- Flights from Des Moines
- Des Moines to Charleston
Flights from Des Moines to Charleston
There are no direct flights from Des Moines to Charleston. The fastest way is one stop via Charlotte or Atlanta, about 3h 29m door to door (88 connections a week on current schedules).
No direct flights · 6 connection options From 3h 29m
Des Moines to Charleston at a glance
Fastest journey3h 29mVia Charlotte, on current schedules
Nonstop flightsNoneConnect via Charlotte or Atlanta
Best ways to fly from Des Moines to Charleston
Ranked by how easy the connection is: one airline or alliance first (bags and connection protected), then the quickest self-transfer options.
1Search
DSM Charlotte (CLT) CHS
Leg 1: American Airlines · Leg 2: American Airlines
Sun07:30 DSM10:30 CLT0h 45m connection11:15 CLT11:59 CHSAmerican Airlines
2Search
DSM Atlanta (ATL) CHS
Leg 1: Delta Air Lines · Leg 2: Delta Air Lines
Mon11:30 DSM14:19 ATL0h 56m connection15:15 ATL16:10 CHSDelta Air Lines
3Search
DSM Chicago (ORD) CHS
Leg 1: American Airlines, United Airlines, SkyWest · Leg 2: American Airlines, United Airlines, SkyWest
Tue08:00 DSM09:21 ORD1h 24m connection10:45 ORD13:43 CHSUnited Airlines
4Search
DSM Nashville (BNA) CHS
Leg 1: Allegiant Air · Leg 2: Southwest Airlines
Mon06:30 DSM07:51 BNA2h 39m connection10:30 BNA12:37 CHSAllegiant Air + Southwest Airlines
5Search
DSM Philadelphia (PHL) CHS
Leg 1: Allegiant Air · Leg 2: American Airlines
Sun14:00 DSM17:16 PHL4h 59m connection22:15 PHL23:39 CHSAllegiant Air + American Airlines
6Search
DSM Orlando (MCO) CHS
Leg 1: Frontier Airlines, Allegiant Air, Breeze Airways · Leg 2: Breeze Airways
Connections are computed from flights actually flown over the last 8 weeks, with at least 45 minutes to change on one airline and 2 hours on separate tickets. Times are local. The search shows live itineraries and exact times.
Good to know
- Distance
- 1,556 km966 miles
- Journey time
- 3h 29mon current schedules
- Time difference
- +1hCharleston vs Des Moines
- Currency in Charleston
- USD
- Airports
- DSM → CHS
Flights from Des Moines to Charleston: questions answered
Are there direct flights from Des Moines to Charleston?
No. There is no nonstop service, so you will connect, most easily in Charlotte, Atlanta and Chicago. Some connections are on one airline or alliance, so your bags and connection are protected on a single ticket.
How long is the flight from Des Moines to Charleston?
With one connection the journey usually takes around 3h 29m, depending on the layover. The straight-line distance is 1,556 km.
Where do you change planes between Des Moines and Charleston?
The best connecting points are Charlotte (CLT), Atlanta (ATL), Chicago (ORD) and Nashville (BNA). American Airlines flies both legs via Charlotte, so you can book it as one ticket.
Which airports serve Des Moines and Charleston?
Des Moines: Des Moines International Airport (DSM). Charleston: Charleston International Airport (CHS).
What is the time difference between Des Moines and Charleston?
Charleston is 1 hour ahead of Des Moines.





