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Flights from Charleston to Des Moines
There are no direct flights from Charleston to Des Moines. The fastest way is one stop via Charlotte or Atlanta, about 3h 31m door to door (133 connections a week on current schedules).
No direct flights · 6 connection options From 3h 31m
Charleston to Des Moines at a glance
Fastest journey3h 31mVia Charlotte, on current schedules
Nonstop flightsNoneConnect via Charlotte or Atlanta
Best ways to fly from Charleston to Des Moines
Ranked by how easy the connection is: one airline or alliance first (bags and connection protected), then the quickest self-transfer options.
1Search
CHS Charlotte (CLT) DSM
Leg 1: American Airlines · Leg 2: American Airlines
Sun21:00 CHS21:39 CLT0h 51m connection22:30 CLT23:31 DSMAmerican Airlines
2Search
CHS Atlanta (ATL) DSM
Leg 1: Delta Air Lines · Leg 2: Delta Air Lines
Wed14:30 CHS15:21 ATL1h 09m connection16:30 ATL17:24 DSMDelta Air Lines
3Search
CHS Chicago (ORD) DSM
Leg 1: American Airlines, United Airlines · Leg 2: American Airlines, United Airlines, SkyWest
Thu17:45 CHS18:51 ORD1h 09m connection20:00 ORD21:06 DSMUnited Airlines
4Search
CHS Orlando (MCO) DSM
Leg 1: Breeze Airways · Leg 2: Frontier Airlines, Allegiant Air, Breeze Airways
Connections are computed from flights actually flown over the last 8 weeks, with at least 45 minutes to change on one airline and 2 hours on separate tickets. Times are local. The search shows live itineraries and exact times.
Good to know
- Distance
- 1,556 km966 miles
- Journey time
- 3h 31mon current schedules
- Time difference
- -1hDes Moines vs Charleston
- Currency in Des Moines
- USD
- Airports
- CHS → DSM
Flights from Charleston to Des Moines: questions answered
Are there direct flights from Charleston to Des Moines?
No. There is no nonstop service, so you will connect, most easily in Charlotte, Atlanta and Chicago. Some connections are on one airline or alliance, so your bags and connection are protected on a single ticket.
How long is the flight from Charleston to Des Moines?
With one connection the journey usually takes around 3h 31m, depending on the layover. The straight-line distance is 1,556 km.
Where do you change planes between Charleston and Des Moines?
The best connecting points are Charlotte (CLT), Atlanta (ATL), Chicago (ORD) and Orlando (MCO). American Airlines flies both legs via Charlotte, so you can book it as one ticket.
Which airports serve Charleston and Des Moines?
Charleston: Charleston International Airport (CHS). Des Moines: Des Moines International Airport (DSM).
What is the time difference between Charleston and Des Moines?
Des Moines is 1 hour behind Charleston.





