- Home
- Flights
- Flights from Des Moines
- Des Moines to Buffalo
Flights from Des Moines to Buffalo
There are no direct flights from Des Moines to Buffalo. The fastest way is one stop via Chicago or Charlotte, about 3h 47m door to door (83 connections a week on current schedules).
No direct flights · 6 connection options From 3h 47m
Des Moines to Buffalo at a glance
Fastest journey3h 47mVia Chicago, on current schedules
Nonstop flightsNoneConnect via Chicago or Charlotte
Best ways to fly from Des Moines to Buffalo
Ranked by how easy the connection is: one airline or alliance first (bags and connection protected), then the quickest self-transfer options.
1Search
DSM Chicago (ORD) BUF
Leg 1: American Airlines, United Airlines, SkyWest · Leg 2: American Airlines, United Airlines, Envoy Air
Fri11:30 DSM12:51 ORD1h 09m connection14:00 ORD16:17 BUFUnited Airlines
2Search
DSM Charlotte (CLT) BUF
Leg 1: American Airlines · Leg 2: American Airlines
Fri13:45 DSM16:45 CLT0h 45m connection17:30 CLT18:52 BUFAmerican Airlines
3Search
DSM Atlanta (ATL) BUF
Leg 1: Delta Air Lines · Leg 2: Delta Air Lines, Frontier Airlines
Sun12:00 DSM14:49 ATL0h 56m connection15:45 ATL17:33 BUFDelta Air Lines
4Search
DSM Nashville (BNA) BUF
Leg 1: Allegiant Air · Leg 2: Southwest Airlines
Thu09:30 DSM10:51 BNA3h 39m connection14:30 BNA16:58 BUFAllegiant Air + Southwest Airlines
Connections are computed from flights actually flown over the last 8 weeks, with at least 45 minutes to change on one airline and 2 hours on separate tickets. Times are local. The search shows live itineraries and exact times.
Good to know
- Distance
- 1,221 km758 miles
- Journey time
- 3h 47mon current schedules
- Time difference
- +1hBuffalo vs Des Moines
- Currency in Buffalo
- USD
- Airports
- DSM → BUF
Flights from Des Moines to Buffalo: questions answered
Are there direct flights from Des Moines to Buffalo?
No. There is no nonstop service, so you will connect, most easily in Chicago, Charlotte and Atlanta. Some connections are on one airline or alliance, so your bags and connection are protected on a single ticket.
How long is the flight from Des Moines to Buffalo?
With one connection the journey usually takes around 3h 47m, depending on the layover. The straight-line distance is 1,221 km.
Where do you change planes between Des Moines and Buffalo?
The best connecting points are Chicago (ORD), Charlotte (CLT), Atlanta (ATL) and Nashville (BNA). American Airlines flies both legs via Chicago, so you can book it as one ticket.
Which airports serve Des Moines and Buffalo?
Des Moines: Des Moines International Airport (DSM). Buffalo: Buffalo Niagara International Airport (BUF).
What is the time difference between Des Moines and Buffalo?
Buffalo is 1 hour ahead of Des Moines.





