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Flights from Buffalo to Des Moines
There are no direct flights from Buffalo to Des Moines. The fastest way is one stop via Chicago or Charlotte, about 3h 51m door to door (76 connections a week on current schedules).
No direct flights · 6 connection options From 3h 51m
Buffalo to Des Moines at a glance
Fastest journey3h 51mVia Chicago, on current schedules
Nonstop flightsNoneConnect via Chicago or Charlotte
Best ways to fly from Buffalo to Des Moines
Ranked by how easy the connection is: one airline or alliance first (bags and connection protected), then the quickest self-transfer options.
1Search
BUF Chicago (ORD) DSM
Leg 1: American Airlines, United Airlines · Leg 2: American Airlines, United Airlines, SkyWest
Wed18:15 BUF18:50 ORD1h 10m connection20:00 ORD21:06 DSMUnited Airlines
2Search
BUF Charlotte (CLT) DSM
Leg 1: American Airlines · Leg 2: American Airlines
Sun06:30 BUF08:01 CLT1h 14m connection09:15 CLT10:16 DSMAmerican Airlines
3Search
BUF Atlanta (ATL) DSM
Leg 1: Delta Air Lines, Frontier Airlines · Leg 2: Delta Air Lines
Mon06:15 BUF08:01 ATL1h 29m connection09:30 ATL10:24 DSMDelta Air Lines
Connections are computed from flights actually flown over the last 8 weeks, with at least 45 minutes to change on one airline and 2 hours on separate tickets. Times are local. The search shows live itineraries and exact times.
Good to know
- Distance
- 1,221 km758 miles
- Journey time
- 3h 51mon current schedules
- Time difference
- -1hDes Moines vs Buffalo
- Currency in Des Moines
- USD
- Airports
- BUF → DSM
Flights from Buffalo to Des Moines: questions answered
Are there direct flights from Buffalo to Des Moines?
No. There is no nonstop service, so you will connect, most easily in Chicago, Charlotte and Atlanta. Some connections are on one airline or alliance, so your bags and connection are protected on a single ticket.
How long is the flight from Buffalo to Des Moines?
With one connection the journey usually takes around 3h 51m, depending on the layover. The straight-line distance is 1,221 km.
Where do you change planes between Buffalo and Des Moines?
The best connecting points are Chicago (ORD), Charlotte (CLT), Atlanta (ATL) and Philadelphia (PHL). American Airlines flies both legs via Chicago, so you can book it as one ticket.
Which airports serve Buffalo and Des Moines?
Buffalo: Buffalo Niagara International Airport (BUF). Des Moines: Des Moines International Airport (DSM).
What is the time difference between Buffalo and Des Moines?
Des Moines is 1 hour behind Buffalo.





