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Flights from Syracuse to Des Moines
There are no direct flights from Syracuse to Des Moines. The fastest way is one stop via Chicago or Charlotte, about 4h 21m door to door (61 connections a week on current schedules).
No direct flights · 6 connection options From 4h 21m
Syracuse to Des Moines at a glance
Fastest journey4h 21mVia Chicago, on current schedules
Nonstop flightsNoneConnect via Chicago or Charlotte
Best ways to fly from Syracuse to Des Moines
Ranked by how easy the connection is: one airline or alliance first (bags and connection protected), then the quickest self-transfer options.
1Search
SYR Chicago (ORD) DSM
Leg 1: American Airlines, United Airlines, SkyWest · Leg 2: American Airlines, United Airlines, SkyWest
Tue17:45 SYR18:47 ORD1h 13m connection20:00 ORD21:06 DSMUnited Airlines
2Search
SYR Charlotte (CLT) DSM
Leg 1: American Airlines · Leg 2: American Airlines
Sun06:15 SYR08:01 CLT1h 14m connection09:15 CLT10:16 DSMAmerican Airlines
3Search
SYR Atlanta (ATL) DSM
Leg 1: Delta Air Lines · Leg 2: Delta Air Lines
Mon06:15 SYR08:19 ATL1h 11m connection09:30 ATL10:24 DSMDelta Air Lines
4Search
SYR Boston (BOS) DSM
Leg 1: JetBlue Airways, Delta Air Lines, Envoy Air · Leg 2: Allegiant Air
Mon07:00 SYR07:56 BOS3h 19m connection11:15 BOS13:10 DSMJetBlue Airways + Allegiant Air
Connections are computed from flights actually flown over the last 8 weeks, with at least 45 minutes to change on one airline and 2 hours on separate tickets. Times are local. The search shows live itineraries and exact times.
Good to know
- Distance
- 1,444 km897 miles
- Journey time
- 4h 21mon current schedules
- Time difference
- -1hDes Moines vs Syracuse
- Currency in Des Moines
- USD
- Airports
- SYR → DSM
Flights from Syracuse to Des Moines: questions answered
Are there direct flights from Syracuse to Des Moines?
No. There is no nonstop service, so you will connect, most easily in Chicago, Charlotte and Atlanta. Some connections are on one airline or alliance, so your bags and connection are protected on a single ticket.
How long is the flight from Syracuse to Des Moines?
With one connection the journey usually takes around 4h 21m, depending on the layover. The straight-line distance is 1,444 km.
Where do you change planes between Syracuse and Des Moines?
The best connecting points are Chicago (ORD), Charlotte (CLT), Atlanta (ATL) and Boston (BOS). American Airlines flies both legs via Chicago, so you can book it as one ticket.
Which airports serve Syracuse and Des Moines?
Syracuse: Syracuse Hancock International Airport (SYR). Des Moines: Des Moines International Airport (DSM).
What is the time difference between Syracuse and Des Moines?
Des Moines is 1 hour behind Syracuse.





