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Flights from St Louis to Santiago
There are no direct flights from St Louis to Santiago. The easiest way is one stop via Philadelphia or Orlando, about 7h 02m door to door.
No direct flights · 4 connection options From 7h 02m
St Louis to Santiago at a glance
Fastest journey7h 02mEstimated
Nonstop flightsNoneConnect via Philadelphia or Orlando
Best ways to fly from St Louis to Santiago
Ranked by how easy the connection is: one airline or alliance first (bags and connection protected), then the quickest self-transfer options.
1Search
STL Philadelphia (PHL) STI
Leg 1: American Airlines, Southwest Airlines · Leg 2: American Airlines, Frontier Airlines
3Search
STL Fort Lauderdale (FLL) STI
Leg 1: Frontier Airlines, Southwest Airlines · Leg 2: JetBlue Airways
Connections are computed from flights actually flown over the last 8 weeks, with at least 45 minutes to change on one airline and 2 hours on separate tickets. Times are local. The search shows live itineraries and exact times.
Good to know
- Distance
- 2,851 km1,770 miles
- Journey time
- 7h 02mestimate
- Time difference
- +2hSantiago vs St Louis
- Currency in Santiago
- USD
- Airports
- STL → STI
Flights from St Louis to Santiago: questions answered
Are there direct flights from St Louis to Santiago?
No. There is no nonstop service, so you will connect, most easily in Philadelphia, Orlando and Fort Lauderdale. Some connections are on one airline or alliance, so your bags and connection are protected on a single ticket.
How long is the flight from St Louis to Santiago?
With one connection the journey usually takes around 7h 02m, depending on the layover. The straight-line distance is 2,851 km.
Where do you change planes between St Louis and Santiago?
The best connecting points are Philadelphia (PHL), Orlando (MCO), Fort Lauderdale (FLL) and San Juan (SJU). American Airlines flies both legs via Philadelphia, so you can book it as one ticket.
Which airports serve St Louis and Santiago?
St Louis: St. Louis Lambert International Airport (STL). Santiago: Cibao International Airport (STI).
What is the time difference between St Louis and Santiago?
Santiago is 2 hours ahead of St Louis.





