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Flights from St Louis to Knoxville
There are no direct flights from St Louis to Knoxville. The fastest way is one stop via Nashville or Atlanta, about 2h 34m door to door (162 connections a week on current schedules).
No direct flights · 4 connection options From 2h 34m
St Louis to Knoxville at a glance
Fastest journey2h 34mVia Nashville, on current schedules
Nonstop flightsNoneConnect via Nashville or Atlanta
Best ways to fly from St Louis to Knoxville
Ranked by how easy the connection is: one airline or alliance first (bags and connection protected), then the quickest self-transfer options.
1Search
STL Nashville (BNA) TYS
Leg 1: Southwest Airlines · Leg 2: Southwest Airlines
Sat08:00 STL08:53 BNA1h 07m connection10:00 BNA11:34 TYSSouthwest Airlines
2Search
STL Atlanta (ATL) TYS
Leg 1: Delta Air Lines, Frontier Airlines, Southwest Airlines · Leg 2: Delta Air Lines, American Airlines
Mon07:00 STL09:20 ATL0h 55m connection10:15 ATL10:58 TYSDelta Air Lines
3Search
STL Chicago (ORD) TYS
Leg 1: American Airlines, United Airlines, GoJet Airlines · Leg 2: United Airlines, Envoy Air, GoJet Airlines
Tue13:00 STL14:13 ORD0h 47m connection15:00 ORD17:25 TYSUnited Airlines
4Search
STL Charlotte (CLT) TYS
Leg 1: American Airlines, Southwest Airlines · Leg 2: American Airlines, Piedmont Airlines (1948-1989), SkyWest
Mon09:30 STL12:05 CLT2h 10m connection14:15 CLT14:55 TYSAmerican Airlines + Piedmont Airlines (1948-1989)
Connections are computed from flights actually flown over the last 8 weeks, with at least 45 minutes to change on one airline and 2 hours on separate tickets. Times are local. The search shows live itineraries and exact times.
Good to know
- Distance
- 629 km391 miles
- Journey time
- 2h 34mon current schedules
- Time difference
- +1hKnoxville vs St Louis
- Currency in Knoxville
- USD
- Airports
- STL → TYS
Flights from St Louis to Knoxville: questions answered
Are there direct flights from St Louis to Knoxville?
No. There is no nonstop service, so you will connect, most easily in Nashville, Atlanta and Chicago. Some connections are on one airline or alliance, so your bags and connection are protected on a single ticket.
How long is the flight from St Louis to Knoxville?
With one connection the journey usually takes around 2h 34m, depending on the layover. The straight-line distance is 629 km.
Where do you change planes between St Louis and Knoxville?
The best connecting points are Nashville (BNA), Atlanta (ATL), Chicago (ORD) and Charlotte (CLT). Southwest Airlines flies both legs via Nashville, so you can book it as one ticket.
Which airports serve St Louis and Knoxville?
St Louis: St. Louis Lambert International Airport (STL). Knoxville: McGhee Tyson Airport (TYS).
What is the time difference between St Louis and Knoxville?
Knoxville is 1 hour ahead of St Louis.
