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Flights from San Francisco to Des Moines
There are no direct flights from San Francisco to Des Moines. The fastest way is one stop via Denver or Las Vegas, about 4h 41m door to door (384 connections a week on current schedules).
No direct flights · 6 connection options From 4h 41m
San Francisco to Des Moines at a glance
Fastest journey4h 41mVia Denver, on current schedules
Nonstop flightsNoneConnect via Denver or Las Vegas
Best ways to fly from San Francisco to Des Moines
Ranked by how easy the connection is: one airline or alliance first (bags and connection protected), then the quickest self-transfer options.
1Search
SFO Denver (DEN) DSM
Leg 1: Frontier Airlines, Southwest Airlines, United Airlines · Leg 2: Frontier Airlines, Southwest Airlines, United Airlines
Tue14:00 SFO17:20 DEN0h 55m connection18:15 DEN20:41 DSMSouthwest Airlines
2Search
SFO Las Vegas (LAS) DSM
Leg 1: Alaska Airlines, Frontier Airlines, Southwest Airlines · Leg 2: Allegiant Air, Southwest Airlines
Sun10:45 SFO12:09 LAS1h 36m connection13:45 LAS18:26 DSMSouthwest Airlines
3Search
SFO Chicago (ORD) DSM
Leg 1: American Airlines, United Airlines · Leg 2: American Airlines, United Airlines, SkyWest
Sat10:15 SFO16:15 ORD0h 45m connection17:00 ORD18:06 DSMUnited Airlines
4Search
SFO Dallas (DFW) DSM
Leg 1: American Airlines, Frontier Airlines, United Airlines · Leg 2: American Airlines
Thu07:30 SFO12:55 DFW0h 50m connection13:45 DFW15:22 DSMAmerican Airlines
5Search
SFO Phoenix (PHX) DSM
Leg 1: American Airlines, Frontier Airlines, Southwest Airlines · Leg 2: American Airlines, Frontier Airlines, Southwest Airlines
Sat08:30 SFO10:22 PHX2h 38m connection13:00 PHX17:34 DSMUnited Airlines + American Airlines
6Search
SFO Houston (IAH) DSM
Leg 1: United Airlines · Leg 2: United Airlines, Mesa Airlines
Thu12:30 SFO18:07 IAH2h 08m connection20:15 IAH22:06 DSMUnited Airlines
Connections are computed from flights actually flown over the last 8 weeks, with at least 45 minutes to change on one airline and 2 hours on separate tickets. Times are local. The search shows live itineraries and exact times.
Good to know
- Distance
- 2,488 km1,545 miles
- Journey time
- 4h 41mon current schedules
- Time difference
- +2hDes Moines vs San Francisco
- Currency in Des Moines
- USD
- Airports
- SFO → DSM
Flights from San Francisco to Des Moines: questions answered
Are there direct flights from San Francisco to Des Moines?
No. There is no nonstop service, so you will connect, most easily in Denver, Las Vegas and Chicago. Some connections are on one airline or alliance, so your bags and connection are protected on a single ticket.
How long is the flight from San Francisco to Des Moines?
With one connection the journey usually takes around 4h 41m, depending on the layover. The straight-line distance is 2,488 km.
Where do you change planes between San Francisco and Des Moines?
The best connecting points are Denver (DEN), Las Vegas (LAS), Chicago (ORD) and Dallas (DFW). Frontier Airlines flies both legs via Denver, so you can book it as one ticket.
Which airports serve San Francisco and Des Moines?
San Francisco: San Francisco International Airport (SFO). Des Moines: Des Moines International Airport (DSM).
What is the time difference between San Francisco and Des Moines?
Des Moines is 2 hours ahead of San Francisco.





