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Flights from San Diego to Knoxville
There are no direct flights from San Diego to Knoxville. The fastest way is one stop via Denver or Nashville, about 5h 31m door to door (264 connections a week on current schedules).
No direct flights · 6 connection options From 5h 31m
San Diego to Knoxville at a glance
Fastest journey5h 31mVia Denver, on current schedules
Nonstop flightsNoneConnect via Denver or Nashville
Best ways to fly from San Diego to Knoxville
Ranked by how easy the connection is: one airline or alliance first (bags and connection protected), then the quickest self-transfer options.
1Search
SAN Denver (DEN) TYS
Leg 1: Alaska Airlines, Frontier Airlines, Southwest Airlines · Leg 2: Allegiant Air, Frontier Airlines, Southwest Airlines
Mon10:15 SAN13:21 DEN0h 54m connection14:15 DEN18:46 TYSSouthwest Airlines
2Search
SAN Nashville (BNA) TYS
Leg 1: Southwest Airlines · Leg 2: Southwest Airlines
Sun12:30 SAN18:12 BNA1h 18m connection19:30 BNA21:04 TYSSouthwest Airlines
3Search
SAN Dallas (DFW) TYS
Leg 1: Alaska Airlines, American Airlines, Frontier Airlines · Leg 2: American Airlines
Mon08:00 SAN12:57 DFW0h 48m connection13:45 DFW16:36 TYSAmerican Airlines
4Search
SAN Atlanta (ATL) TYS
Leg 1: Delta Air Lines · Leg 2: Delta Air Lines, American Airlines
Mon06:30 SAN13:37 ATL0h 53m connection14:30 ATL15:13 TYSDelta Air Lines
5Search
SAN Chicago (ORD) TYS
Leg 1: Alaska Airlines, American Airlines, Frontier Airlines · Leg 2: United Airlines, Envoy Air, GoJet Airlines
Tue06:45 SAN12:36 ORD1h 39m connection14:15 ORD16:40 TYSUnited Airlines
6Search
SAN Austin (AUS) TYS
Leg 1: Alaska Airlines, Frontier Airlines, Southwest Airlines · Leg 2: Allegiant Air, Southwest Airlines
Sun06:30 SAN11:10 AUS2h 50m connection14:00 AUS17:07 TYSSouthwest Airlines + Allegiant Air
Connections are computed from flights actually flown over the last 8 weeks, with at least 45 minutes to change on one airline and 2 hours on separate tickets. Times are local. The search shows live itineraries and exact times.
Good to know
- Distance
- 3,058 km1,899 miles
- Journey time
- 5h 31mon current schedules
- Time difference
- +3hKnoxville vs San Diego
- Currency in Knoxville
- USD
- Airports
- SAN, CLD → TYS
Flights from San Diego to Knoxville: questions answered
Are there direct flights from San Diego to Knoxville?
No. There is no nonstop service, so you will connect, most easily in Denver, Nashville and Dallas. Some connections are on one airline or alliance, so your bags and connection are protected on a single ticket.
How long is the flight from San Diego to Knoxville?
With one connection the journey usually takes around 5h 31m, depending on the layover. The straight-line distance is 3,058 km.
Where do you change planes between San Diego and Knoxville?
The best connecting points are Denver (DEN), Nashville (BNA), Dallas (DFW) and Atlanta (ATL). Alaska Airlines flies both legs via Denver, so you can book it as one ticket.
Which airports serve San Diego and Knoxville?
San Diego: San Diego International Airport (SAN) and McClellan-Palomar Airport (CLD). Knoxville: McGhee Tyson Airport (TYS).
What is the time difference between San Diego and Knoxville?
Knoxville is 3 hours ahead of San Diego.





