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Flights from San Diego to Des Moines
There are no direct flights from San Diego to Des Moines. The fastest way is one stop via Denver or Phoenix, about 4h 26m door to door (311 connections a week on current schedules).
No direct flights · 6 connection options From 4h 26m
San Diego to Des Moines at a glance
Fastest journey4h 26mVia Denver, on current schedules
Nonstop flightsNoneConnect via Denver or Phoenix
Best ways to fly from San Diego to Des Moines
Ranked by how easy the connection is: one airline or alliance first (bags and connection protected), then the quickest self-transfer options.
1Search
SAN Denver (DEN) DSM
Leg 1: Alaska Airlines, Frontier Airlines, Southwest Airlines · Leg 2: Frontier Airlines, Southwest Airlines, United Airlines
Mon07:30 SAN10:36 DEN0h 54m connection11:30 DEN13:56 DSMSouthwest Airlines
2Search
SAN Phoenix (PHX) DSM
Leg 1: Alaska Airlines, American Airlines, Frontier Airlines · Leg 2: American Airlines, Frontier Airlines, Southwest Airlines
Tue06:30 SAN07:44 PHX0h 46m connection08:30 PHX13:04 DSMAmerican Airlines
3Search
SAN Las Vegas (LAS) DSM
Leg 1: Alaska Airlines, Frontier Airlines, Southwest Airlines · Leg 2: Allegiant Air, Southwest Airlines
Sat09:15 SAN10:23 LAS0h 52m connection11:15 LAS15:56 DSMSouthwest Airlines
4Search
SAN Dallas (DFW) DSM
Leg 1: Alaska Airlines, American Airlines, Frontier Airlines · Leg 2: American Airlines
Thu08:00 SAN12:57 DFW0h 48m connection13:45 DFW15:22 DSMAmerican Airlines
5Search
SAN Chicago (ORD) DSM
Leg 1: Alaska Airlines, American Airlines, Frontier Airlines · Leg 2: American Airlines, United Airlines, SkyWest
Sun06:30 SAN12:21 ORD0h 54m connection13:15 ORD14:21 DSMUnited Airlines
6Search
SAN Houston (IAH) DSM
Leg 1: United Airlines · Leg 2: United Airlines, Mesa Airlines
Thu12:00 SAN17:04 IAH3h 11m connection20:15 IAH22:06 DSMUnited Airlines
Connections are computed from flights actually flown over the last 8 weeks, with at least 45 minutes to change on one airline and 2 hours on separate tickets. Times are local. The search shows live itineraries and exact times.
Good to know
- Distance
- 2,297 km1,426 miles
- Journey time
- 4h 26mon current schedules
- Time difference
- +2hDes Moines vs San Diego
- Currency in Des Moines
- USD
- Airports
- SAN, CLD → DSM
Flights from San Diego to Des Moines: questions answered
Are there direct flights from San Diego to Des Moines?
No. There is no nonstop service, so you will connect, most easily in Denver, Phoenix and Las Vegas. Some connections are on one airline or alliance, so your bags and connection are protected on a single ticket.
How long is the flight from San Diego to Des Moines?
With one connection the journey usually takes around 4h 26m, depending on the layover. The straight-line distance is 2,297 km.
Where do you change planes between San Diego and Des Moines?
The best connecting points are Denver (DEN), Phoenix (PHX), Las Vegas (LAS) and Dallas (DFW). Alaska Airlines flies both legs via Denver, so you can book it as one ticket.
Which airports serve San Diego and Des Moines?
San Diego: San Diego International Airport (SAN) and McClellan-Palomar Airport (CLD). Des Moines: Des Moines International Airport (DSM).
What is the time difference between San Diego and Des Moines?
Des Moines is 2 hours ahead of San Diego.





