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Flights from Panama City to San Francisco
There are no direct flights from Panama City to San Francisco. The fastest way is one stop via Denver or Dallas, about 6h 16m door to door (93 connections a week on current schedules).
No direct flights · 6 connection options From 6h 16m
Panama City to San Francisco at a glance
Fastest journey6h 16mVia Denver, on current schedules
Nonstop flightsNoneConnect via Denver or Dallas
Best ways to fly from Panama City to San Francisco
Ranked by how easy the connection is: one airline or alliance first (bags and connection protected), then the quickest self-transfer options.
1Search
ECP Denver (DEN) SFO
Leg 1: Southwest Airlines, United Airlines · Leg 2: Frontier Airlines, Southwest Airlines, United Airlines
Mon10:15 ECP12:03 DEN0h 57m connection13:00 DEN14:31 SFOSouthwest Airlines
2Search
ECP Dallas (DFW) SFO
Leg 1: American Airlines, Envoy Air · Leg 2: American Airlines, Frontier Airlines, United Airlines
Mon16:30 ECP18:26 DFW0h 49m connection19:15 DFW20:48 SFOAmerican Airlines
3Search
ECP Atlanta (ATL) SFO
Leg 1: Delta Air Lines · Leg 2: Delta Air Lines, Frontier Airlines, United Airlines
Tue11:15 ECP13:04 ATL0h 56m connection14:00 ATL15:51 SFODelta Air Lines
4Search
ECP St Louis (STL) SFO
Leg 1: Southwest Airlines · Leg 2: Southwest Airlines, United Airlines
Sun06:00 ECP07:30 STL1h 00m connection08:30 STL10:38 SFOSouthwest Airlines
5Search
ECP Nashville (BNA) SFO
Leg 1: Southwest Airlines · Leg 2: Southwest Airlines, United Airlines
Tue11:45 ECP12:52 BNA1h 23m connection14:15 BNA16:37 SFOSouthwest Airlines
6Search
ECP Austin (AUS) SFO
Leg 1: Southwest Airlines, Delta Air Lines, SkyWest · Leg 2: Delta Air Lines, Southwest Airlines, United Airlines
Sat15:30 ECP17:25 AUS2h 05m connection19:30 AUS21:06 SFODelta Air Lines + United Airlines
Connections are computed from flights actually flown over the last 8 weeks, with at least 45 minutes to change on one airline and 2 hours on separate tickets. Times are local. The search shows live itineraries and exact times.
Good to know
- Distance
- 3,470 km2,155 miles
- Journey time
- 6h 16mon current schedules
- Time difference
- -2hSan Francisco vs Panama City
- Currency in San Francisco
- USD
- Airports
- ECP → SFO
Flights from Panama City to San Francisco: questions answered
Are there direct flights from Panama City to San Francisco?
No. There is no nonstop service, so you will connect, most easily in Denver, Dallas and Atlanta. Some connections are on one airline or alliance, so your bags and connection are protected on a single ticket.
How long is the flight from Panama City to San Francisco?
With one connection the journey usually takes around 6h 16m, depending on the layover. The straight-line distance is 3,470 km.
Where do you change planes between Panama City and San Francisco?
The best connecting points are Denver (DEN), Dallas (DFW), Atlanta (ATL) and St Louis (STL). Southwest Airlines flies both legs via Denver, so you can book it as one ticket.
Which airports serve Panama City and San Francisco?
Panama City: Northwest Florida Beaches International Airport (ECP). San Francisco: San Francisco International Airport (SFO).
What is the time difference between Panama City and San Francisco?
San Francisco is 2 hours behind Panama City.





