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Flights from Panama City to Des Moines
There are no direct flights from Panama City to Des Moines. The fastest way is one stop via Atlanta or Chicago, about 3h 39m door to door (60 connections a week on current schedules).
No direct flights · 6 connection options From 3h 39m
Panama City to Des Moines at a glance
Fastest journey3h 39mVia Atlanta, on current schedules
Nonstop flightsNoneConnect via Atlanta or Chicago
Best ways to fly from Panama City to Des Moines
Ranked by how easy the connection is: one airline or alliance first (bags and connection protected), then the quickest self-transfer options.
1Search
ECP Atlanta (ATL) DSM
Leg 1: Delta Air Lines · Leg 2: Delta Air Lines
Tue11:15 ECP13:04 ATL0h 56m connection14:00 ATL14:54 DSMDelta Air Lines
2Search
ECP Chicago (MDW) DSM
Leg 1: Southwest Airlines · Leg 2: Southwest Airlines
Sat14:45 ECP16:40 MDW1h 20m connection18:00 MDW18:54 DSMSouthwest Airlines
3Search
ECP Dallas (DFW) DSM
Leg 1: American Airlines, Envoy Air · Leg 2: American Airlines
Mon16:30 ECP18:26 DFW3h 04m connection21:30 DFW23:07 DSMAmerican Airlines
Connections are computed from flights actually flown over the last 8 weeks, with at least 45 minutes to change on one airline and 2 hours on separate tickets. Times are local. The search shows live itineraries and exact times.
Good to know
- Distance
- 1,458 km905 miles
- Journey time
- 3h 39mon current schedules
- Time difference
- NoneDes Moines vs Panama City
- Currency in Des Moines
- USD
- Airports
- ECP → DSM
Flights from Panama City to Des Moines: questions answered
Are there direct flights from Panama City to Des Moines?
No. There is no nonstop service, so you will connect, most easily in Atlanta, Chicago and Dallas. Some connections are on one airline or alliance, so your bags and connection are protected on a single ticket.
How long is the flight from Panama City to Des Moines?
With one connection the journey usually takes around 3h 39m, depending on the layover. The straight-line distance is 1,458 km.
Where do you change planes between Panama City and Des Moines?
The best connecting points are Atlanta (ATL), Chicago (MDW), Dallas (DFW) and Charlotte (CLT). Delta Air Lines flies both legs via Atlanta, so you can book it as one ticket.
Which airports serve Panama City and Des Moines?
Panama City: Northwest Florida Beaches International Airport (ECP). Des Moines: Des Moines International Airport (DSM).





