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Flights from Missoula to Knoxville
There are no direct flights from Missoula to Knoxville. The fastest way is one stop via Denver or Chicago, about 5h 36m door to door (18 connections a week on current schedules).
No direct flights · 4 connection options From 5h 36m
Missoula to Knoxville at a glance
Fastest journey5h 36mVia Denver, on current schedules
Nonstop flightsNoneConnect via Denver or Chicago
Best ways to fly from Missoula to Knoxville
Ranked by how easy the connection is: one airline or alliance first (bags and connection protected), then the quickest self-transfer options.
1Search
MSO Denver (DEN) TYS
Leg 1: United Airlines, SkyWest · Leg 2: Allegiant Air, Frontier Airlines, Southwest Airlines
Tue15:00 MSO16:54 DEN1h 06m connection18:00 DEN22:36 TYSUnited Airlines
2Search
MSO Chicago (ORD) TYS
Leg 1: United Airlines, Envoy Air · Leg 2: United Airlines, Envoy Air, GoJet Airlines
Tue12:30 MSO16:34 ORD2h 26m connection19:00 ORD21:25 TYSUnited Airlines
3Search
MSO Dallas (DFW) TYS
Leg 1: American Airlines, Envoy Air · Leg 2: American Airlines
Mon13:00 MSO17:07 DFW3h 08m connection20:15 DFW23:06 TYSEnvoy Air + American Airlines
Connections are computed from flights actually flown over the last 8 weeks, with at least 45 minutes to change on one airline and 2 hours on separate tickets. Times are local. The search shows live itineraries and exact times.
Good to know
- Distance
- 2,763 km1,716 miles
- Journey time
- 5h 36mon current schedules
- Time difference
- +2hKnoxville vs Missoula
- Currency in Knoxville
- USD
- Airports
- MSO → TYS
Flights from Missoula to Knoxville: questions answered
Are there direct flights from Missoula to Knoxville?
No. There is no nonstop service, so you will connect, most easily in Denver, Chicago and Dallas. Some connections are on one airline or alliance, so your bags and connection are protected on a single ticket.
How long is the flight from Missoula to Knoxville?
With one connection the journey usually takes around 5h 36m, depending on the layover. The straight-line distance is 2,763 km.
Where do you change planes between Missoula and Knoxville?
The best connecting points are Denver (DEN), Chicago (ORD), Dallas (DFW) and Las Vegas (LAS). United Airlines flies both legs via Denver, so you can book it as one ticket.
Which airports serve Missoula and Knoxville?
Missoula: Missoula Montana Airport (MSO). Knoxville: McGhee Tyson Airport (TYS).
What is the time difference between Missoula and Knoxville?
Knoxville is 2 hours ahead of Missoula.





