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Flights from Mexico City to Santa Cruz
There are no direct flights from Mexico City to Santa Cruz. The easiest way is one stop via Lima or Panama City, about 9h 50m door to door.
No direct flights · 4 connection options From 9h 50m
Mexico City to Santa Cruz at a glance
Fastest journey9h 50mEstimated
Nonstop flightsNoneConnect via Lima or Panama City
Best ways to fly from Mexico City to Santa Cruz
Ranked by how easy the connection is: one airline or alliance first (bags and connection protected), then the quickest self-transfer options.
1Search
MEX Lima (LIM) SRZ
Leg 1: Aeroméxico, LATAM Airlines Peru, Volaris · Leg 2: Boliviana de Aviación, LATAM Airlines Peru
2Search
MEX Panama City (PTY) SRZ
Leg 1: Aeroméxico, Copa Airlines · Leg 2: Boliviana de Aviación, Copa Airlines
4Search
MEX Miami (MIA) SRZ
Leg 1: Aeroméxico, American Airlines, Volaris · Leg 2: Boliviana de Aviación
Connections are computed from flights actually flown over the last 8 weeks, with at least 45 minutes to change on one airline and 2 hours on separate tickets. Times are local. The search shows live itineraries and exact times.
Good to know
- Distance
- 5,707 km3,544 miles
- Journey time
- 9h 50mestimate
- Time difference
- +2hSanta Cruz vs Mexico City
- Currency in Santa Cruz
- USD
- Airports
- MEX, NLU, TLC → VVI
Flights from Mexico City to Santa Cruz: questions answered
Are there direct flights from Mexico City to Santa Cruz?
No. There is no nonstop service, so you will connect, most easily in Lima, Panama City and Bogota. Some connections are on one airline or alliance, so your bags and connection are protected on a single ticket.
How long is the flight from Mexico City to Santa Cruz?
With one connection the journey usually takes around 9h 50m, depending on the layover. The straight-line distance is 5,707 km.
Where do you change planes between Mexico City and Santa Cruz?
The best connecting points are Lima (LIM), Panama City (PTY), Bogota (BOG) and Miami (MIA). Aeroméxico flies both legs via Lima, so you can book it as one ticket.
Which airports serve Mexico City and Santa Cruz?
Mexico City: Mexico City Benito Juárez International Airport (MEX), Felipe Ángeles International Airport (NLU) and Adolfo López Mateos International Airport (TLC). Santa Cruz: Viru Viru International Airport (VVI).
What is the time difference between Mexico City and Santa Cruz?
Santa Cruz is 2 hours ahead of Mexico City.
