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Flights from Medellin to Santa Cruz
There are no direct flights from Medellin to Santa Cruz. The easiest way is one stop via Bogota or Lima, about 6h 13m door to door.
No direct flights · 3 connection options From 6h 13m
Medellin to Santa Cruz at a glance
Fastest journey6h 13mEstimated
Nonstop flightsNoneConnect via Bogota or Lima
Best ways to fly from Medellin to Santa Cruz
Ranked by how easy the connection is: one airline or alliance first (bags and connection protected), then the quickest self-transfer options.
2Search
MDE Lima (LIM) SRZ
Leg 1: LATAM Airlines Peru · Leg 2: Boliviana de Aviación, LATAM Airlines Peru
3Search
MDE Panama City (PTY) SRZ
Leg 1: Copa Airlines, Copa Airlines Colombia · Leg 2: Boliviana de Aviación, Copa Airlines
Connections are computed from flights actually flown over the last 8 weeks, with at least 45 minutes to change on one airline and 2 hours on separate tickets. Times are local. The search shows live itineraries and exact times.
Good to know
- Distance
- 3,002 km1,864 miles
- Journey time
- 6h 13mestimate
- Time difference
- +1hSanta Cruz vs Medellin
- Currency in Santa Cruz
- USD
- Airports
- MDE, EOH → VVI
Flights from Medellin to Santa Cruz: questions answered
Are there direct flights from Medellin to Santa Cruz?
No. There is no nonstop service, so you will connect, most easily in Bogota, Lima and Panama City. Some connections are on one airline or alliance, so your bags and connection are protected on a single ticket.
How long is the flight from Medellin to Santa Cruz?
With one connection the journey usually takes around 6h 13m, depending on the layover. The straight-line distance is 3,002 km.
Where do you change planes between Medellin and Santa Cruz?
The best connecting points are Bogota (BOG), Lima (LIM) and Panama City (PTY). Avianca flies both legs via Bogota, so you can book it as one ticket.
Which airports serve Medellin and Santa Cruz?
Medellin: Jose Maria Córdova International Airport (MDE) and Enrique Olaya Herrera Airport (EOH). Santa Cruz: Viru Viru International Airport (VVI).
What is the time difference between Medellin and Santa Cruz?
Santa Cruz is 1 hour ahead of Medellin.





