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Flights from Manchester to St Louis
There are no direct flights from Manchester to St Louis. The fastest way is one stop via Chicago or Nashville, about 3h 46m door to door (50 connections a week on current schedules).
No direct flights · 6 connection options From 3h 46m
Manchester to St Louis at a glance
Fastest journey3h 46mVia Chicago, on current schedules
Nonstop flightsNoneConnect via Chicago or Nashville
Best ways to fly from Manchester to St Louis
Ranked by how easy the connection is: one airline or alliance first (bags and connection protected), then the quickest self-transfer options.
1Search
MHT Chicago (MDW) STL
Leg 1: Southwest Airlines · Leg 2: Southwest Airlines
Sat08:00 MHT09:10 MDW0h 50m connection10:00 MDW10:46 STLSouthwest Airlines
2Search
MHT Nashville (BNA) STL
Leg 1: Southwest Airlines · Leg 2: Southwest Airlines
Sun11:45 MHT13:08 BNA0h 52m connection14:00 BNA14:50 STLSouthwest Airlines
3Search
MHT Baltimore (BWI) STL
Leg 1: Southwest Airlines · Leg 2: Southwest Airlines
Sat12:15 MHT13:35 BWI0h 55m connection14:30 BWI15:26 STLSouthwest Airlines
4Search
MHT Philadelphia (PHL) STL
Leg 1: Piedmont Airlines (1948-1989) · Leg 2: American Airlines, Southwest Airlines
Sat10:30 MHT11:41 PHL4h 19m connection16:00 PHL17:01 STLPiedmont Airlines (1948-1989) + American Airlines
5Search
MHT Raleigh (RDU) STL
Leg 1: Breeze Airways · Leg 2: Southwest Airlines
Thu12:30 MHT14:20 RDU5h 55m connection20:15 RDU21:04 STLBreeze Airways + Southwest Airlines
Connections are computed from flights actually flown over the last 8 weeks, with at least 45 minutes to change on one airline and 2 hours on separate tickets. Times are local. The search shows live itineraries and exact times.
Good to know
- Distance
- 1,646 km1,022 miles
- Journey time
- 3h 46mon current schedules
- Time difference
- -1hSt Louis vs Manchester
- Currency in St Louis
- USD
- Airports
- MHT → STL
Flights from Manchester to St Louis: questions answered
Are there direct flights from Manchester to St Louis?
No. There is no nonstop service, so you will connect, most easily in Chicago, Nashville and Baltimore. Some connections are on one airline or alliance, so your bags and connection are protected on a single ticket.
How long is the flight from Manchester to St Louis?
With one connection the journey usually takes around 3h 46m, depending on the layover. The straight-line distance is 1,646 km.
Where do you change planes between Manchester and St Louis?
The best connecting points are Chicago (MDW), Nashville (BNA), Baltimore (BWI) and Philadelphia (PHL). Southwest Airlines flies both legs via Chicago, so you can book it as one ticket.
Which airports serve Manchester and St Louis?
Manchester: Manchester-Boston Regional Airport (MHT). St Louis: St. Louis Lambert International Airport (STL).
What is the time difference between Manchester and St Louis?
St Louis is 1 hour behind Manchester.





