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Flights from Louisville to Panama City
There are no direct flights from Louisville to Panama City. The fastest way is one stop via Tampa or Atlanta, about 16h 34m door to door (1 connection a week on current schedules).
No direct flights · 6 connection options From 6h 38m
Louisville to Panama City at a glance
Fastest journey6h 38mVia Tampa, on current schedules
Nonstop flightsNoneConnect via Tampa or Atlanta
Best ways to fly from Louisville to Panama City
Ranked by how easy the connection is: one airline or alliance first (bags and connection protected), then the quickest self-transfer options.
1Search
SDF Tampa (TPA) PTY
Leg 1: Breeze Airways, Southwest Airlines · Leg 2: Copa Airlines
Sun15:45 SDF17:28 TPA11h 47m connection05:15 TPA07:19 PTYSouthwest Airlines + Copa Airlines
Connections are computed from flights actually flown over the last 8 weeks, with at least 45 minutes to change on one airline and 2 hours on separate tickets. Times are local. The search shows live itineraries and exact times.
Good to know
- Distance
- 3,313 km2,057 miles
- Journey time
- 6h 38mon current schedules
- Time difference
- NonePanama City vs Louisville
- Currency in Panama City
- USD
- Airports
- SDF → PTY
Flights from Louisville to Panama City: questions answered
Are there direct flights from Louisville to Panama City?
No. There is no nonstop service, so you will connect, most easily in Tampa, Atlanta and Miami. Some connections are on one airline or alliance, so your bags and connection are protected on a single ticket.
How long is the flight from Louisville to Panama City?
With one connection the journey usually takes around 6h 38m, depending on the layover. The straight-line distance is 3,313 km.
Where do you change planes between Louisville and Panama City?
The best connecting points are Tampa (TPA), Atlanta (ATL), Miami (MIA) and Fort Lauderdale (FLL). Compare one-ticket itineraries with self-transfer options in the search.
Which airports serve Louisville and Panama City?
Louisville: Louisville Muhammad Ali International Airport (SDF). Panama City: Tocumen International Airport (PTY).





