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Flights from Louisville to La Crosse
There are no direct flights from Louisville to La Crosse. The fastest way is one stop via Chicago or Minneapolis, about 8h 39m door to door (3 connections a week on current schedules).
No direct flights · 2 connection options From 4h 57m
Louisville to La Crosse at a glance
Fastest journey4h 57mVia Chicago, on current schedules
Nonstop flightsNoneConnect via Chicago or Minneapolis
Best ways to fly from Louisville to La Crosse
Ranked by how easy the connection is: one airline or alliance first (bags and connection protected), then the quickest self-transfer options.
1Search
SDF Chicago (ORD) LSE
Leg 1: Republic Airlines, SkyWest, Envoy Air · Leg 2: Envoy Air
Mon10:15 SDF10:21 ORD6h 39m connection17:00 ORD17:54 LSERepublic Airlines + Envoy Air
Connections are computed from flights actually flown over the last 8 weeks, with at least 45 minutes to change on one airline and 2 hours on separate tickets. Times are local. The search shows live itineraries and exact times.
Good to know
- Distance
- 771 km479 miles
- Journey time
- 4h 57mon current schedules
- Time difference
- -1hLa Crosse vs Louisville
- Currency in La Crosse
- USD
- Airports
- SDF → LSE
Flights from Louisville to La Crosse: questions answered
Are there direct flights from Louisville to La Crosse?
No. There is no nonstop service, so you will connect, most easily in Chicago and Minneapolis. Some connections are on one airline or alliance, so your bags and connection are protected on a single ticket.
How long is the flight from Louisville to La Crosse?
With one connection the journey usually takes around 4h 57m, depending on the layover. The straight-line distance is 771 km.
Where do you change planes between Louisville and La Crosse?
The best connecting points are Chicago (ORD) and Minneapolis (MSP). Republic Airlines flies both legs via Chicago, so you can book it as one ticket.
Which airports serve Louisville and La Crosse?
Louisville: Louisville Muhammad Ali International Airport (SDF). La Crosse: La Crosse Regional Airport (LSE).
What is the time difference between Louisville and La Crosse?
La Crosse is 1 hour behind Louisville.





