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Flights from La Crosse to Des Moines
There are no direct flights from La Crosse to Des Moines. The fastest way is one stop via Chicago, about 4h 36m door to door (2 connections a week on current schedules).
No direct flights · 1 connection option From 4h 36m
La Crosse to Des Moines at a glance
Fastest journey4h 36mVia Chicago, on current schedules
Nonstop flightsNoneConnect via Chicago
Best ways to fly from La Crosse to Des Moines
Ranked by how easy the connection is: one airline or alliance first (bags and connection protected), then the quickest self-transfer options.
1Search
LSE Chicago (ORD) DSM
Leg 1: Envoy Air · Leg 2: American Airlines, United Airlines, SkyWest
Sat12:30 LSE13:33 ORD2h 27m connection16:00 ORD17:06 DSMEnvoy Air + United Airlines
Connections are computed from flights actually flown over the last 8 weeks, with at least 45 minutes to change on one airline and 2 hours on separate tickets. Times are local. The search shows live itineraries and exact times.
Good to know
- Distance
- 314 km195 miles
- Journey time
- 4h 36mon current schedules
- Time difference
- NoneDes Moines vs La Crosse
- Currency in Des Moines
- USD
- Airports
- LSE → DSM
Flights from La Crosse to Des Moines: questions answered
Are there direct flights from La Crosse to Des Moines?
No. There is no nonstop service, so you will connect, most easily in Chicago. Most connections mean separate tickets, so leave plenty of time to collect bags and check in again.
How long is the flight from La Crosse to Des Moines?
With one connection the journey usually takes around 4h 36m, depending on the layover. The straight-line distance is 314 km.
Where do you change planes between La Crosse and Des Moines?
The best connecting points are Chicago (ORD). Compare one-ticket itineraries with self-transfer options in the search.
Which airports serve La Crosse and Des Moines?
La Crosse: La Crosse Regional Airport (LSE). Des Moines: Des Moines International Airport (DSM).





