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Flights from Greenville to Buffalo
There are no direct flights from Greenville to Buffalo. The fastest way is one stop via Baltimore or Atlanta, about 2h 56m door to door (104 connections a week on current schedules).
No direct flights · 6 connection options From 2h 56m
Greenville to Buffalo at a glance
Fastest journey2h 56mVia Baltimore, on current schedules
Nonstop flightsNoneConnect via Baltimore or Atlanta
Best ways to fly from Greenville to Buffalo
Ranked by how easy the connection is: one airline or alliance first (bags and connection protected), then the quickest self-transfer options.
1Search
GSP Baltimore (BWI) BUF
Leg 1: Southwest Airlines · Leg 2: Southwest Airlines
Thu08:45 GSP09:55 BWI0h 50m connection10:45 BWI11:41 BUFSouthwest Airlines
2Search
GSP Atlanta (ATL) BUF
Leg 1: Delta Air Lines · Leg 2: Delta Air Lines, Frontier Airlines
Mon11:30 GSP12:08 ATL0h 52m connection13:00 ATL14:48 BUFDelta Air Lines
3Search
GSP Nashville (BNA) BUF
Leg 1: Southwest Airlines · Leg 2: Southwest Airlines
Thu13:30 GSP13:20 BNA1h 10m connection14:30 BNA16:58 BUFSouthwest Airlines
4Search
GSP Chicago (ORD) BUF
Leg 1: United Airlines, GoJet Airlines, Envoy Air · Leg 2: American Airlines, United Airlines, Envoy Air
Mon10:45 GSP11:26 ORD2h 49m connection14:15 ORD16:32 BUFGoJet Airlines + United Airlines
5Search
GSP Detroit (DTW) BUF
Leg 1: Delta Air Lines · Leg 2: Delta Air Lines, SkyWest
Mon07:15 GSP08:36 DTW5h 39m connection14:15 DTW15:07 BUFDelta Air Lines + SkyWest
6Search
GSP Charlotte (CLT) BUF
Leg 1: American Airlines, Piedmont Airlines (1948-1989) · Leg 2: American Airlines
Sun21:00 GSP21:29 CLT11h 46m connection09:15 CLT10:37 BUFAmerican Airlines
Connections are computed from flights actually flown over the last 8 weeks, with at least 45 minutes to change on one airline and 2 hours on separate tickets. Times are local. The search shows live itineraries and exact times.
Good to know
- Distance
- 943 km586 miles
- Journey time
- 2h 56mon current schedules
- Time difference
- NoneBuffalo vs Greenville
- Currency in Buffalo
- USD
- Airports
- GSP → BUF
Flights from Greenville to Buffalo: questions answered
Are there direct flights from Greenville to Buffalo?
No. There is no nonstop service, so you will connect, most easily in Baltimore, Atlanta and Nashville. Some connections are on one airline or alliance, so your bags and connection are protected on a single ticket.
How long is the flight from Greenville to Buffalo?
With one connection the journey usually takes around 2h 56m, depending on the layover. The straight-line distance is 943 km.
Where do you change planes between Greenville and Buffalo?
The best connecting points are Baltimore (BWI), Atlanta (ATL), Nashville (BNA) and Chicago (ORD). Southwest Airlines flies both legs via Baltimore, so you can book it as one ticket.
Which airports serve Greenville and Buffalo?
Greenville: Greenville-Spartanburg International Airport (GSP). Buffalo: Buffalo Niagara International Airport (BUF).





