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Flights from Columbia to Knoxville
There are no direct flights from Columbia to Knoxville. The fastest way is one stop via Chicago or Charlotte, about 4h 00m door to door (7 connections a week on current schedules).
No direct flights · 2 connection options From 4h 00m
Columbia to Knoxville at a glance
Fastest journey4h 00mVia Chicago, on current schedules
Nonstop flightsNoneConnect via Chicago or Charlotte
Best ways to fly from Columbia to Knoxville
Ranked by how easy the connection is: one airline or alliance first (bags and connection protected), then the quickest self-transfer options.
1Search
COU Chicago (ORD) TYS
Leg 1: SkyWest, Envoy Air, GoJet Airlines · Leg 2: United Airlines, Envoy Air, GoJet Airlines
Sat10:45 COU11:47 ORD1h 43m connection13:30 ORD15:45 TYSEnvoy Air
2Search
COU Charlotte (CLT) TYS
Leg 1: Envoy Air · Leg 2: American Airlines, Piedmont Airlines (1948-1989), SkyWest
Mon07:30 COU10:06 CLT4h 09m connection14:15 CLT14:55 TYSEnvoy Air + Piedmont Airlines (1948-1989)
Connections are computed from flights actually flown over the last 8 weeks, with at least 45 minutes to change on one airline and 2 hours on separate tickets. Times are local. The search shows live itineraries and exact times.
Good to know
- Distance
- 798 km496 miles
- Journey time
- 4h 00mon current schedules
- Time difference
- +1hKnoxville vs Columbia
- Currency in Knoxville
- USD
- Airports
- COU → TYS
Flights from Columbia to Knoxville: questions answered
Are there direct flights from Columbia to Knoxville?
No. There is no nonstop service, so you will connect, most easily in Chicago and Charlotte. Some connections are on one airline or alliance, so your bags and connection are protected on a single ticket.
How long is the flight from Columbia to Knoxville?
With one connection the journey usually takes around 4h 00m, depending on the layover. The straight-line distance is 798 km.
Where do you change planes between Columbia and Knoxville?
The best connecting points are Chicago (ORD) and Charlotte (CLT). SkyWest flies both legs via Chicago, so you can book it as one ticket.
Which airports serve Columbia and Knoxville?
Columbia: Columbia Regional Airport (COU). Knoxville: McGhee Tyson Airport (TYS).
What is the time difference between Columbia and Knoxville?
Knoxville is 1 hour ahead of Columbia.





