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Flights from Cleveland to Greenville
There are no direct flights from Cleveland to Greenville. The fastest way is one stop via Charlotte or Atlanta, about 2h 54m door to door (176 connections a week on current schedules).
No direct flights · 6 connection options From 2h 54m
Cleveland to Greenville at a glance
Fastest journey2h 54mVia Charlotte, on current schedules
Nonstop flightsNoneConnect via Charlotte or Atlanta
Best ways to fly from Cleveland to Greenville
Ranked by how easy the connection is: one airline or alliance first (bags and connection protected), then the quickest self-transfer options.
1Search
CLE Charlotte (CLT) GSP
Leg 1: American Airlines · Leg 2: American Airlines
Mon16:45 CLE18:03 CLT1h 12m connection19:15 CLT19:39 GSPAmerican Airlines
2Search
CLE Atlanta (ATL) GSP
Leg 1: Delta Air Lines, Frontier Airlines · Leg 2: Delta Air Lines
Mon07:15 CLE08:46 ATL0h 59m connection09:45 ATL10:27 GSPDelta Air Lines
3Search
CLE Nashville (BNA) GSP
Leg 1: Frontier Airlines, Southwest Airlines · Leg 2: Southwest Airlines
Tue13:15 CLE13:29 BNA1h 16m connection14:45 BNA16:34 GSPSouthwest Airlines
4Search
CLE Baltimore (BWI) GSP
Leg 1: Southwest Airlines · Leg 2: Southwest Airlines
Tue15:45 CLE16:47 BWI1h 13m connection18:00 BWI19:15 GSPSouthwest Airlines
5Search
CLE Chicago (ORD) GSP
Leg 1: American Airlines, United Airlines, Republic Airlines · Leg 2: United Airlines, GoJet Airlines, Envoy Air
Sat12:30 CLE12:44 ORD1h 31m connection14:15 ORD16:40 GSPSkyWest
6Search
CLE Washington (IAD) GSP
Leg 1: United Airlines, GoJet Airlines, Mesa Airlines · Leg 2: CommutAir, Mesa Airlines
Sat06:00 CLE07:03 IAD5h 27m connection12:30 IAD13:50 GSPUnited Airlines + Mesa Airlines
Connections are computed from flights actually flown over the last 8 weeks, with at least 45 minutes to change on one airline and 2 hours on separate tickets. Times are local. The search shows live itineraries and exact times.
Good to know
- Distance
- 742 km461 miles
- Journey time
- 2h 54mon current schedules
- Time difference
- NoneGreenville vs Cleveland
- Currency in Greenville
- USD
- Airports
- CLE → GSP
Flights from Cleveland to Greenville: questions answered
Are there direct flights from Cleveland to Greenville?
No. There is no nonstop service, so you will connect, most easily in Charlotte, Atlanta and Nashville. Some connections are on one airline or alliance, so your bags and connection are protected on a single ticket.
How long is the flight from Cleveland to Greenville?
With one connection the journey usually takes around 2h 54m, depending on the layover. The straight-line distance is 742 km.
Where do you change planes between Cleveland and Greenville?
The best connecting points are Charlotte (CLT), Atlanta (ATL), Nashville (BNA) and Baltimore (BWI). American Airlines flies both legs via Charlotte, so you can book it as one ticket.
Which airports serve Cleveland and Greenville?
Cleveland: Cleveland Hopkins International Airport (CLE). Greenville: Greenville-Spartanburg International Airport (GSP).





