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Flights from Cape Girardeau to Buffalo
There are no direct flights from Cape Girardeau to Buffalo. The fastest way is one stop via Chicago, about 5h 17m door to door (6 connections a week on current schedules).
No direct flights · 1 connection option From 5h 17m
Cape Girardeau to Buffalo at a glance
Fastest journey5h 17mVia Chicago, on current schedules
Nonstop flightsNoneConnect via Chicago
Best ways to fly from Cape Girardeau to Buffalo
Ranked by how easy the connection is: one airline or alliance first (bags and connection protected), then the quickest self-transfer options.
1Search
CGI Chicago (ORD) BUF
Leg 1: Contour Airlines · Leg 2: American Airlines, United Airlines, Envoy Air
Fri10:00 CGI11:12 ORD2h 48m connection14:00 ORD16:17 BUFContour Airlines + United Airlines
Connections are computed from flights actually flown over the last 8 weeks, with at least 45 minutes to change on one airline and 2 hours on separate tickets. Times are local. The search shows live itineraries and exact times.
Good to know
- Distance
- 1,105 km686 miles
- Journey time
- 5h 17mon current schedules
- Time difference
- +1hBuffalo vs Cape Girardeau
- Currency in Buffalo
- USD
- Airports
- CGI → BUF
Flights from Cape Girardeau to Buffalo: questions answered
Are there direct flights from Cape Girardeau to Buffalo?
No. There is no nonstop service, so you will connect, most easily in Chicago. Most connections mean separate tickets, so leave plenty of time to collect bags and check in again.
How long is the flight from Cape Girardeau to Buffalo?
With one connection the journey usually takes around 5h 17m, depending on the layover. The straight-line distance is 1,105 km.
Where do you change planes between Cape Girardeau and Buffalo?
The best connecting points are Chicago (ORD). Compare one-ticket itineraries with self-transfer options in the search.
Which airports serve Cape Girardeau and Buffalo?
Cape Girardeau: Cape Girardeau Regional Airport (CGI). Buffalo: Buffalo Niagara International Airport (BUF).
What is the time difference between Cape Girardeau and Buffalo?
Buffalo is 1 hour ahead of Cape Girardeau.





